Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases
We propose a guideline about the risk, prevention and treatment of infection in the patient under immunomodulatory or immunosuppressive therapy in the context of autoimmune or autoinflammatory disease. It is divided into three sections: drugs and associated risk of infection; immunizations; risk, pr...
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2021-06-01
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doaj-9acc1446852645ab94ec625522b2c2322021-06-01T07:41:14ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582021-06-0134646948310.20344/amp.156255410Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune DiseasesSofia R. Valdoleiros0Isabel Furtado1Carolina Silva2Inês Correia Gonçalves3André Santos Silva4Olga Vasconcelos5Ana Aboim Horta6A. Ludgero Vasconcelos7Sandra Xará8Maria João Gonçalves9Miguel Araújo Abreu10Rui Sarmento-Castro11Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto. Centro de Diagnóstico Pneumológico de Vila Nova de Gaia. Vila Nova de Gaia.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto. Escola de Medicina. Universidade do Minho. Braga.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto.Serviço de Doenças Infeciosas. Centro Hospitalar Universitário do Porto. Porto. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto.We propose a guideline about the risk, prevention and treatment of infection in the patient under immunomodulatory or immunosuppressive therapy in the context of autoimmune or autoinflammatory disease. It is divided into three sections: drugs and associated risk of infection; immunizations; risk, prevention, and treatment of specific infections. The treatment of autoimmune diseases involves the use of immunosuppressive or immunomodulatory therapies, with an increasing number of new drugs being used. It is associated with an increased risk of infection, which may be present globally or only for specific agents, varying widely depending on the pharmacological class and even within the same class. The prevention strategy and clinical management need to be individually tailored and there are several key factors: characterization of the disease that prompts the immunosuppression, understanding of the mechanism of action of the immunosuppressive drug, knowledge of previous infections, recognition of risk factors, laboratory test results, vaccine administration, monitoring of clinical signs and symptoms and patient education.https://actamedicaportuguesa.com/revista/index.php/amp/article/view/15625doenças autoimunes/terapêutica farmacológicadoenças preveníveis por vacinaimunossupressoresinfeções/prevenção & controloinfeções/terapêutica farmacológica |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sofia R. Valdoleiros Isabel Furtado Carolina Silva Inês Correia Gonçalves André Santos Silva Olga Vasconcelos Ana Aboim Horta A. Ludgero Vasconcelos Sandra Xará Maria João Gonçalves Miguel Araújo Abreu Rui Sarmento-Castro |
spellingShingle |
Sofia R. Valdoleiros Isabel Furtado Carolina Silva Inês Correia Gonçalves André Santos Silva Olga Vasconcelos Ana Aboim Horta A. Ludgero Vasconcelos Sandra Xará Maria João Gonçalves Miguel Araújo Abreu Rui Sarmento-Castro Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases Acta Médica Portuguesa doenças autoimunes/terapêutica farmacológica doenças preveníveis por vacina imunossupressores infeções/prevenção & controlo infeções/terapêutica farmacológica |
author_facet |
Sofia R. Valdoleiros Isabel Furtado Carolina Silva Inês Correia Gonçalves André Santos Silva Olga Vasconcelos Ana Aboim Horta A. Ludgero Vasconcelos Sandra Xará Maria João Gonçalves Miguel Araújo Abreu Rui Sarmento-Castro |
author_sort |
Sofia R. Valdoleiros |
title |
Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases |
title_short |
Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases |
title_full |
Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases |
title_fullStr |
Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases |
title_full_unstemmed |
Guideline for the Treatment and Prevention of Infections Associated with Immunosuppressive Therapy for Autoimmune Diseases |
title_sort |
guideline for the treatment and prevention of infections associated with immunosuppressive therapy for autoimmune diseases |
publisher |
Ordem dos Médicos |
series |
Acta Médica Portuguesa |
issn |
0870-399X 1646-0758 |
publishDate |
2021-06-01 |
description |
We propose a guideline about the risk, prevention and treatment of infection in the patient under immunomodulatory or immunosuppressive therapy in the context of autoimmune or autoinflammatory disease. It is divided into three sections: drugs and associated risk of infection; immunizations; risk, prevention, and treatment of specific infections. The treatment of autoimmune diseases involves the use of immunosuppressive or immunomodulatory therapies, with an increasing number of new drugs being used. It is associated with an increased risk of infection, which may be present globally or only for specific agents, varying widely depending on the pharmacological class and even within the same class. The prevention strategy and clinical management need to be individually tailored and there are several key factors: characterization of the disease that prompts the immunosuppression, understanding of the mechanism of action of the immunosuppressive drug, knowledge of previous infections, recognition of risk factors, laboratory test results, vaccine administration, monitoring of clinical signs and symptoms and patient education. |
topic |
doenças autoimunes/terapêutica farmacológica doenças preveníveis por vacina imunossupressores infeções/prevenção & controlo infeções/terapêutica farmacológica |
url |
https://actamedicaportuguesa.com/revista/index.php/amp/article/view/15625 |
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