Effect of epinephrine on the absorption of lidocaine following application to the oral mucosa in rats

Abstract Background We investigated the role of epinephrine in prolonging the localization of lidocaine on the oral mucosa and inhibiting its absorption in the blood of rats. Methods We used 7–8-week-old pathogen-free Wistar male rats (n = 128) for our study. We divided them into the control group a...

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Bibliographic Details
Main Authors: Rui Sasaki, Katsuhisa Sunada
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-021-01691-0