PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology.

With the recent emergence of a novel pandemic strain, there is presently intense interest in understanding the molecular signatures of virulence of influenza viruses. PB1-F2 proteins from epidemiologically important influenza A virus strains were studied to determine their function and contribution...

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Bibliographic Details
Main Authors: Julie L McAuley, Jerry E Chipuk, Kelli L Boyd, Nick Van De Velde, Douglas R Green, Jonathan A McCullers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2908617?pdf=render