Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats
Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics. Whether diabetics with CVSP also benefit from this drug, however, is unknown. We evaluate...
Main Authors: | Maria J. Crespo, Marie Roman, Jonathan Matias, Myrna Morales, Hector Torres, Jose Quidgley |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2018-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2018/9790303 |
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