Cardiac toxicity of fluoroquinolones and bedaquiline
The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented. The article demonstrates the importance of concomitan...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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NEW TERRA Publishing House
2019-05-01
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| Series: | Tuberkulez i Bolezni Lëgkih |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1264 |
| Summary: | The review analyzes data on the impact of fluoroquinolones and bedaquiline on the cardiac conduction system. The dependence of the cardiotoxic effect of fluoroquinolones on their influence on the potassium channels of cardiomyocytes is presented. The article demonstrates the importance of concomitant factors (potassium level in the blood, concurrent heart disorders, a genetically determined amount of HERG receptors in the myocardium, concomitant drug therapy) in the development of the cardiac toxicity caused by fluoroquinolones and bedaquiline. |
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| ISSN: | 2075-1230 2542-1506 |