Maximal sum of metabolic exchange fluxes outperforms biomass yield as a predictor of growth rate of microorganisms.
Growth rate has long been considered one of the most valuable phenotypes that can be measured in cells. Aside from being highly accessible and informative in laboratory cultures, maximal growth rate is often a prime determinant of cellular fitness, and predicting phenotypes that underlie fitness is...
Main Authors: | Raphy Zarecki, Matthew A Oberhardt, Keren Yizhak, Allon Wagner, Ella Shtifman Segal, Shiri Freilich, Christopher S Henry, Uri Gophna, Eytan Ruppin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4035307?pdf=render |
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