Pulmonary Alveolar Proteinosis with Respiratory Failure-Anaesthetic Management of Whole Lung Lavage

• Main Authors: Sunita Nandkumar, Madhavi Desai, Manju Butani, Z Udwadia
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2009-01-01
• Series: Indian Journal of Anaesthesia
• Subjects: Pulmonary alveolar proteinosis; Whole lung lavage; Broncho-pulmonary lavage; Anaesthesia
• Online Access: http://www.ijaweb.org/article.asp?issn=0019-5049;year=2009;volume=53;issue=3;spage=362;epage=366;aulast=Nandkumar

Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by accumulation of amorphous acellular phospholipid material in the lungs. Whole lung lavage is the standard therapy which gives dramatic clinical improve-ment and offers a long term survival to these patients. A 43-year-old man suffering from PAP presented to casualty with NYHA grade IV dyspnoea with oxygen saturation (SaO 2 ) on pulseoximetry 67% on room air and 78% with O 2 6 L/min. He underwent whole lung lavage under general anaesthesia using one lung ventilation with 37 F left end bronchial double lumen tube. The lung lavage was initially performed for the left lung and for the right lung 4 days later. The patient was discharged home with oxygen saturation of 96 % on room air.