Comorbidity of chronic pain and depression in neurological patients

• Main Author: Gyuzel Rafkatovna Tabeeva
• Format: Article
• Language: Russian
• Published: IMA-PRESS LLC 2013-11-01
• Series: Nevrologiâ, Nejropsihiatriâ, Psihosomatika
• Subjects: chronic pain; depression; comorbidity; neurological diseases
• Online Access: https://nnp.ima-press.net/nnp/article/view/260

The paper presents the literature review of chronic pain syndromes concurrent with depression. Chronic pain and depression have a mutual impact on clinical manifestation, course and treatment effectiveness in these patients. When there is a multitude of neurological, somatic, and autonomic disorders characteristic for the concurrence of pain and depression, understanding the nature of this comorbidity, as well as its diagnosis and treatment priorities assumes an importance. The complexity of detecting the affective symptoms proper in these patients determines less favorable outcomes, chronic persistent pain, the development of therapeutic resistance, and the risk of disease recurrence. The epidemiology and clinical manifestations of chronic pain and depression in the most common neurological diseases are discussed. The current concepts of the pathogenesis of comorbidity of chronic pain and depression and the problems of psychopharmacology are considered.