Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

Background: New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was previously recommended. Country decision makers have to decide whether to further expand eligibility for antiretroviral ther...

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Main Authors: Jeffrey W Eaton, PhD, Nicolas A Menzies, MPH, John Stover, MA, Valentina Cambiano, MS, Leonid Chindelevitch, PhD, Anne Cori, PhD, Jan A C Hontelez, PhD, Salal Humair, PhD, Cliff C Kerr, PhD, Daniel J Klein, PhD, Sharmistha Mishra, MD, Kate M Mitchell, PhD, Brooke E Nichols, MS, Prof. Peter Vickerman, DPhil, Roel Bakker, PhD, Till Bärnighausen, DSc, Anna Bershteyn, PhD, Prof. David E Bloom, PhD, Marie-Claude Boily, PhD, Stewart T Chang, PhD, Ted Cohen, DPH, Peter J Dodd, PhD, Prof. Christophe Fraser, PhD, Chaitra Gopalappa, PhD, Prof. Jens Lundgren, DMSc, Natasha K Martin, DPhil, Evelinn Mikkelsen, MSc, Elisa Mountain, MSc, Quang D Pham, MD, Michael Pickles, PhD, Prof. Andrew Phillips, PhD, Lucy Platt, PhD, Carel Pretorius, PhD, Holly J Prudden, MSc, Prof. Joshua A Salomon, PhD, David A M C van de Vijver, PhD, Sake J de Vlas, PhD, Bradley G Wagner, PhD, Richard G White, PhD, David P Wilson, PhD, Lei Zhang, PhD, John Blandford, PhD, Gesine Meyer-Rath, PhD, Michelle Remme, MSc, Paul Revill, PhD, Nalinee Sangrujee, PhD, Fern Terris-Prestholt, PhD, Meg Doherty, PhD, Nathan Shaffer, MD, Prof. Philippa J Easterbrook, MD, Gottfried Hirnschall, MD, Prof. Timothy B Hallett, PhD
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X13701724

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http://www.sciencedirect.com/science/article/pii/S2214109X13701724

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