the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.
Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to pathogenic microbes. We observed that the ferritin concentration within oral epit...
Main Authors: | Ricardo S Almeida, Sascha Brunke, Antje Albrecht, Sascha Thewes, Michael Laue, John E Edwards, Scott G Filler, Bernhard Hube |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-11-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2581891?pdf=render |
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