STUDIES ON EXTRAINTESTINAL AMEBIASIS IN IRAN BY SEROLOGIC METHODS

Sera from ninety one patients clinically suspected to extra intestinal amoebiasis (ex-am) were collected and examined for presence of anti Entamoeba histolytica (E.h) antibody. The tests were Indirect Immunofluorescence antibody, (IFA or IIF), Gel Diffusion (GD) and counter Immuno Electrophoresis (C...

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Bibliographic Details
Main Authors: H. Motazedian, M. Rezaian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2000-06-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/1712
Description
Summary:Sera from ninety one patients clinically suspected to extra intestinal amoebiasis (ex-am) were collected and examined for presence of anti Entamoeba histolytica (E.h) antibody. The tests were Indirect Immunofluorescence antibody, (IFA or IIF), Gel Diffusion (GD) and counter Immuno Electrophoresis (CIEP). Thirty one patients (34%) had anti E.h. antibody titres of >1:80. Among them eight patients (9%) had acute infection. IFA titres of > 1:640 were found to be significant for differentiation of present infection from past. The sensitivity, specificity, negative and positive predictive value of this test was 100%, 98%, 100% and 89%, respectively. In GD or CIEP tests 13 positive cases (12%) were detected.
ISSN:2251-6085
2251-6093