Primary versus secondary source of data in observational studies and heterogeneity in meta-analyses of drug effects: a survey of major medical journals

Abstract Background The data from individual observational studies included in meta-analyses of drug effects are collected either from ad hoc methods (i.e. “primary data”) or databases that were established for non-research purposes (i.e. “secondary data”). The use of secondary sources may be prone...

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Bibliographic Details
Main Authors: Guillermo Prada-Ramallal, Fatima Roque, Maria Teresa Herdeiro, Bahi Takkouche, Adolfo Figueiras
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-018-0561-3