Microbial translocation is associated with extensive immune activation in dengue virus infected patients with severe disease.

Microbial translocation is associated with extensive immune activation in dengue virus infected patients with severe disease.

BACKGROUND: Severe dengue virus (DENV) disease is associated with extensive immune activation, characterized by a cytokine storm. Previously, elevated lipopolysaccharide (LPS) levels in dengue were found to correlate with clinical disease severity. In the present cross-sectional study we identified...

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Bibliographic Details
Main Authors: Cornelia A M van de Weg, Cláudio S Pannuti, Evaldo S A de Araújo, Henk-Jan van den Ham, Arno C Andeweg, Lucy S V Boas, Alvina C Felix, Karina I Carvalho, Andreia M de Matos, José E Levi, Camila M Romano, Cristiane C Centrone, Celia L de Lima Rodrigues, Expedito Luna, Eric C M van Gorp, Albert D M E Osterhaus, Byron E E Martina, Esper G Kallas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3662706?pdf=render

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