Targeting viral antigens to CD11c on dendritic cells induces retrovirus-specific T cell responses.

Dendritic cells (DC) represent the most potent antigen presenting cells and induce efficient cytotoxic T lymphocyte (CTL) responses against viral infections. Targeting antigens (Ag) to receptors on DCs is a promising strategy to enhance antitumor and antiviral immune responses induced by DCs. Here,...

Full description

Bibliographic Details
Main Authors: Asim Ejaz, Christoph G Ammann, Roland Werner, Georg Huber, Verena Oberhauser, Susanne Hörl, Simone Schimmer, Ulf Dittmer, Dorothee von Laer, Heribert Stoiber, Zoltán Bánki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028784/pdf/?tool=EBI