Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study
Background. In order to reduce stroke risk, left atrial appendage amputation (LAAA) is widely adopted in recent years. The effect of LAAA on left atrial (LA) function remains unknown. The objective of present study was to assess the effect of LAAA on LA function. Methods. Sixteen patients with parox...
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doaj-9c09eec19f6f4a23a4cb90d7e3588c682020-11-24T22:39:01ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/318901318901Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot StudyGijs E. De Maat0Stefano Benussi1Yoran M. Hummel2Sebastien Krul3Alberto Pozzoli4Antoine H. G. Driessen5Massimo A. Mariani6Isabelle C. Van Gelder7Wim-Jan Van Boven8Joris R. de Groot9Department of Cardio-Thoracic Surgery, University Medical Center Groningen, 9711 RB Groningen, NetherlandsDepartment of Cardiac Surgery, San Raffaele University Hospital, Milan, ItalyDepartment of Cardiology, University Medical Center Groningen, 9711 RB Groningen, NetherlandsDepartment of Cardiology, Academic Medical Center, Amsterdam, NetherlandsDepartment of Cardiac Surgery, San Raffaele University Hospital, Milan, ItalyDepartment of Cardio-Thoracic Surgery, Academic Medical Center, Amsterdam, NetherlandsDepartment of Cardio-Thoracic Surgery, University Medical Center Groningen, 9711 RB Groningen, NetherlandsDepartment of Cardiology, University Medical Center Groningen, 9711 RB Groningen, NetherlandsDepartment of Cardio-Thoracic Surgery, Academic Medical Center, Amsterdam, NetherlandsDepartment of Cardiology, Academic Medical Center, Amsterdam, NetherlandsBackground. In order to reduce stroke risk, left atrial appendage amputation (LAAA) is widely adopted in recent years. The effect of LAAA on left atrial (LA) function remains unknown. The objective of present study was to assess the effect of LAAA on LA function. Methods. Sixteen patients with paroxysmal AF underwent thoracoscopic, surgical PVI with LAAA (LAAA group), and were retrospectively matched with 16 patients who underwent the same procedure without LAA amputation (non-LAAA group). To objectify LA function, transthoracic echocardiography with 2D Speckle Tracking was performed before surgery and at 12 months follow-up. Results. Mean age was 57 ± 9 years, 84% were male. Baseline characteristics did not differ significantly except for systolic blood pressure (p=0.005). In both groups, the contractile LA function and LA ejection fraction were not significantly reduced. However, the conduit and reservoir function were significantly decreased at follow-up, compared to baseline. The reduction of strain and strain rate was not significantly different between groups. Conclusions. In this retrospective, observational matched group comparison with a convenience sample size of 16 patients, findings suggest that LAAA does not impair the contractile LA function when compared to patients in which the appendage was unaddressed. However, the LA conduit and reservoir function are reduced in both the LAAA and non-LAAA group. Our data suggest that the LAA can be removed without late LA functional consequences.http://dx.doi.org/10.1155/2015/318901 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Gijs E. De Maat Stefano Benussi Yoran M. Hummel Sebastien Krul Alberto Pozzoli Antoine H. G. Driessen Massimo A. Mariani Isabelle C. Van Gelder Wim-Jan Van Boven Joris R. de Groot |
spellingShingle |
Gijs E. De Maat Stefano Benussi Yoran M. Hummel Sebastien Krul Alberto Pozzoli Antoine H. G. Driessen Massimo A. Mariani Isabelle C. Van Gelder Wim-Jan Van Boven Joris R. de Groot Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study BioMed Research International |
author_facet |
Gijs E. De Maat Stefano Benussi Yoran M. Hummel Sebastien Krul Alberto Pozzoli Antoine H. G. Driessen Massimo A. Mariani Isabelle C. Van Gelder Wim-Jan Van Boven Joris R. de Groot |
author_sort |
Gijs E. De Maat |
title |
Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study |
title_short |
Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study |
title_full |
Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study |
title_fullStr |
Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study |
title_full_unstemmed |
Surgical Left Atrial Appendage Exclusion Does Not Impair Left Atrial Contraction Function: A Pilot Study |
title_sort |
surgical left atrial appendage exclusion does not impair left atrial contraction function: a pilot study |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2015-01-01 |
description |
Background. In order to reduce stroke risk, left atrial appendage amputation (LAAA) is widely adopted in recent years. The effect of LAAA on left atrial (LA) function remains unknown. The objective of present study was to assess the effect of LAAA on LA function. Methods. Sixteen patients with paroxysmal AF underwent thoracoscopic, surgical PVI with LAAA (LAAA group), and were retrospectively matched with 16 patients who underwent the same procedure without LAA amputation (non-LAAA group). To objectify LA function, transthoracic echocardiography with 2D Speckle Tracking was performed before surgery and at 12 months follow-up. Results. Mean age was 57 ± 9 years, 84% were male. Baseline characteristics did not differ significantly except for systolic blood pressure (p=0.005). In both groups, the contractile LA function and LA ejection fraction were not significantly reduced. However, the conduit and reservoir function were significantly decreased at follow-up, compared to baseline. The reduction of strain and strain rate was not significantly different between groups. Conclusions. In this retrospective, observational matched group comparison with a convenience sample size of 16 patients, findings suggest that LAAA does not impair the contractile LA function when compared to patients in which the appendage was unaddressed. However, the LA conduit and reservoir function are reduced in both the LAAA and non-LAAA group. Our data suggest that the LAA can be removed without late LA functional consequences. |
url |
http://dx.doi.org/10.1155/2015/318901 |
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