Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data
Dental caries and periodontitis are among the most common medical conditions. Here, the authors report a GWAS for measures of oral health that reveals 47 risk loci for caries, find genetic correlation with 31 other complex traits and use Mendelian randomization analyses to explore potential causal r...
Main Authors: | Dmitry Shungin, Simon Haworth, Kimon Divaris, Cary S. Agler, Yoichiro Kamatani, Myoung Keun Lee, Kelsey Grinde, George Hindy, Viivi Alaraudanjoki, Paula Pesonen, Alexander Teumer, Birte Holtfreter, Saori Sakaue, Jun Hirata, Yau-Hua Yu, Paul M. Ridker, Franco Giulianini, Daniel I. Chasman, Patrik K. E. Magnusson, Takeaki Sudo, Yukinori Okada, Uwe Völker, Thomas Kocher, Vuokko Anttonen, Marja-Liisa Laitala, Marju Orho-Melander, Tamar Sofer, John R. Shaffer, Alexandre Vieira, Mary L. Marazita, Michiaki Kubo, Yasushi Furuichi, Kari E. North, Steve Offenbacher, Erik Ingelsson, Paul W. Franks, Nicholas J. Timpson, Ingegerd Johansson |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10630-1 |
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