Bactericidal and cytotoxic properties of green synthesized nanosilver using Rosmarinus officinalis leaves
Green synthesized nanoparticles from plant extracts are being used in various biomedical applications, particularly because of their bactericidal and cytotoxic activities. In this study, silver nanoparticles (AgNPs) were successfully synthesized from the...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2020-05-01
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Series: | Green Processing and Synthesis |
Subjects: | |
Online Access: | https://doi.org/10.1515/gps-2020-0025 |
Summary: | Green synthesized nanoparticles from plant extracts are being used in various
biomedical applications, particularly because of their bactericidal and cytotoxic
activities. In this study, silver nanoparticles (AgNPs) were successfully synthesized
from the Rosmarinus officinalis aqueous leaf extract. Different
spectroscopic and microscopic analyses such as ultraviolet-visible (UV-vis)
spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron
microscopy, and energy-dispersive X-ray spectroscopy were performed to verify the
biosynthesized AgNPs in our sample. The formation of nanosilver particles was
preliminarily confirmed by UV-vis spectroscopy at 400 nm. The presence of
carboxylic or amide groups was confirmed by FTIR, for the reduction of the silver
ion. Transmission electron microscopy confirmed a particle size of
12–22 nm. The prepared AgNPs showed good antibacterial activity against
human pathogens and good cytotoxic activity against the human breast cancer cell line
(MDA MB 231). The nanoparticles prepared from R. officinalis can be
used for various biomedical applications. |
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ISSN: | 2191-9542 2191-9550 |