Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study

Studies on long-term exposure to foods/nutrients and its associations with fracture risk are scarce. Using data from the China Health and Nutrition Survey (CHNS), we determined the prospective association of dietary and nutrient patterns with fractures. Data from 15,572 adults aged ≥18 years were an...

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Main Authors: Yohannes Adama Melaku, Tiffany K. Gill, Sarah L. Appleton, Anne W. Taylor, Robert Adams, Zumin Shi
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/9/11/1198
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spelling doaj-9c605b6570a14f80aa806ba1309b329a2020-11-24T20:48:26ZengMDPI AGNutrients2072-66432017-10-01911119810.3390/nu9111198nu9111198Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up StudyYohannes Adama Melaku0Tiffany K. Gill1Sarah L. Appleton2Anne W. Taylor3Robert Adams4Zumin Shi5Adelaide Medical School, The University of Adelaide, Adelaide, SA 5005, AustraliaAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, AustraliaThe Health Observatory, Discipline of Medicine, The Queen Elizabeth Hospital Campus, University of Adelaide, Woodville, SA 5011, AustraliaAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, AustraliaThe Health Observatory, Discipline of Medicine, The Queen Elizabeth Hospital Campus, University of Adelaide, Woodville, SA 5011, AustraliaAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, AustraliaStudies on long-term exposure to foods/nutrients and its associations with fracture risk are scarce. Using data from the China Health and Nutrition Survey (CHNS), we determined the prospective association of dietary and nutrient patterns with fractures. Data from 15,572 adults aged ≥18 years were analyzed. Fracture occurrence was self-reported and dietary intake data were collected using a 24-h recall method for three consecutive days, for each individual across nine waves (1989–2011). We used cumulative and overall mean, recent and baseline dietary and nutrient exposures. Hazard ratios (HR) were used to determine the associations. Two dietary (traditional and modern) and two nutrient (plant- and animal-sourced) patterns were identified. After adjusting for potential confounders, study participants in the third tertiles (highest intake) of the modern dietary and animal-sourced nutrient patterns’ cumulative scores had a 34% (HR = 1.34; 95% CI: 1.06–1.71) and 37% (HR = 1.37; 95% CI: 1.08–1.72) increase in fracture risks compared to those in the first tertiles, respectively. While the overall mean factor scores of dietary and nutrient patterns had a similar (or stronger) pattern of association as the cumulative scores, no association between recent and baseline scores and fracture was found. Greater adherence to a modern dietary and/or an animal-sourced nutrient pattern is associated with a higher risk of total fractures. This suggests that a modern animal based diet is related to bone fragility. A repeated three-day 24-h recall dietary assessment provides a stronger association with fracture compared to a recent or baseline exposure.https://www.mdpi.com/2072-6643/9/11/1198dietary patternnutrient patternfractureChina Health and Nutrition Survey
collection DOAJ
language English
format Article
sources DOAJ
author Yohannes Adama Melaku
Tiffany K. Gill
Sarah L. Appleton
Anne W. Taylor
Robert Adams
Zumin Shi
spellingShingle Yohannes Adama Melaku
Tiffany K. Gill
Sarah L. Appleton
Anne W. Taylor
Robert Adams
Zumin Shi
Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
Nutrients
dietary pattern
nutrient pattern
fracture
China Health and Nutrition Survey
author_facet Yohannes Adama Melaku
Tiffany K. Gill
Sarah L. Appleton
Anne W. Taylor
Robert Adams
Zumin Shi
author_sort Yohannes Adama Melaku
title Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
title_short Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
title_full Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
title_fullStr Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
title_full_unstemmed Prospective Associations of Dietary and Nutrient Patterns with Fracture Risk: A 20-Year Follow-Up Study
title_sort prospective associations of dietary and nutrient patterns with fracture risk: a 20-year follow-up study
publisher MDPI AG
series Nutrients
issn 2072-6643
publishDate 2017-10-01
description Studies on long-term exposure to foods/nutrients and its associations with fracture risk are scarce. Using data from the China Health and Nutrition Survey (CHNS), we determined the prospective association of dietary and nutrient patterns with fractures. Data from 15,572 adults aged ≥18 years were analyzed. Fracture occurrence was self-reported and dietary intake data were collected using a 24-h recall method for three consecutive days, for each individual across nine waves (1989–2011). We used cumulative and overall mean, recent and baseline dietary and nutrient exposures. Hazard ratios (HR) were used to determine the associations. Two dietary (traditional and modern) and two nutrient (plant- and animal-sourced) patterns were identified. After adjusting for potential confounders, study participants in the third tertiles (highest intake) of the modern dietary and animal-sourced nutrient patterns’ cumulative scores had a 34% (HR = 1.34; 95% CI: 1.06–1.71) and 37% (HR = 1.37; 95% CI: 1.08–1.72) increase in fracture risks compared to those in the first tertiles, respectively. While the overall mean factor scores of dietary and nutrient patterns had a similar (or stronger) pattern of association as the cumulative scores, no association between recent and baseline scores and fracture was found. Greater adherence to a modern dietary and/or an animal-sourced nutrient pattern is associated with a higher risk of total fractures. This suggests that a modern animal based diet is related to bone fragility. A repeated three-day 24-h recall dietary assessment provides a stronger association with fracture compared to a recent or baseline exposure.
topic dietary pattern
nutrient pattern
fracture
China Health and Nutrition Survey
url https://www.mdpi.com/2072-6643/9/11/1198
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