Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.
<h4>Objective</h4>Increasing evidence shows that TGF-β1 is a key mediator in diabetic nephropathy (DN) and induces renal fibrosis positively by Smad3 but negatively by Smad7. However, treatment of DN by blocking the TGF-β/Smad pathway remains limited. The present study investigated the a...
Main Authors: | Ting Ting Zhao, Hao Jun Zhang, Xiao Guang Lu, Xiao Ru Huang, Wei Ku Zhang, Hua Wang, Hui Yao Lan, Ping Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24646636/pdf/?tool=EBI |
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