The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

The generation of induced pluripotent stem cells for macular degeneration as a drug screening platform: identification of curcumin as a protective agent for retinal pigment epithelial cells against oxidative stress

Age-related macular degeneration (AMD) is one retinal aging process that may lead to irreversible vision loss in the elderly. Its pathogenesis remains unclear, but oxidative stress inducing retinal pigment epithelial (RPE) cells damage is perhaps responsible for the aging sequence of retina and may...

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Bibliographic Details
Main Authors: Yun-Ching eChang, Wei-Chao eChang, Kuo-Hsuan eHung, Der-Ming eYang, Yi-Wen eLiao, Yung-Hsin eCheng, Lin-Chung eWoung, Ching-Yao eTsai, Chih-Chien eHsu, Tai-Chi eLin, Jorn-Hon eLiu, Shih-Hwa eChiou, Chi-Hsien ePeng, Shih-Jen eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Curcumin
Oxidative Stress
antioxidant
age-related macular degeneration
patient-specific induced pluripotent stem cells
retinal pigment epithelial
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00191/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00191/full

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