The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis

The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis

Abstract Background Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed as sJIA in China. So we speculate that MEFV is critical genetic backg...

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Bibliographic Details
Main Authors: Linqing Zhong, Wei Wang, Ji Li, Mingsheng Ma, Lijuan Gou, Changyan Wang, Zhongxun Yu, Tiannan Zhang, Yanqing Dong, Qijiao Wei, Hongmei Song
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Pediatric Rheumatology Online Journal
Subjects:
MEFV gene
Systemic juvenile idiopathic arthritis
Disease risk
Disease severity
Online Access:http://link.springer.com/article/10.1186/s12969-020-00427-8

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