Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS...

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Main Authors:	Stefanie Gierer, Heike Hofmann-Winkler, Waleed H. Albuali, Stephanie Bertram, Abdullah M. Al-Rubaish, Abdullah A. Yousef, Awatif N. Al-Nafaie, Amein K. Al-Ali, Obeid E. Obeid, Khaled R. Alkharsah, Stefan Pöhlmann
Format:	Article
Language:	English
Published:	Centers for Disease Control and Prevention 2013-12-01
Series:	Emerging Infectious Diseases
Subjects:	MERS coronavirus neutralizing antibodies Saudi Arabia spike pseudotyping MERS-CoV
Online Access:	https://wwwnc.cdc.gov/eid/article/19/12/13-0701_article

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spelling	doaj-9cde62cc61d64eb181ac0548c6680c312020-11-25T02:13:58ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-12-0119122034203610.3201/eid1912.130701Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi ArabiaStefanie GiererHeike Hofmann-WinklerWaleed H. AlbualiStephanie BertramAbdullah M. Al-RubaishAbdullah A. YousefAwatif N. Al-NafaieAmein K. Al-AliObeid E. ObeidKhaled R. AlkharsahStefan PöhlmannWe used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.https://wwwnc.cdc.gov/eid/article/19/12/13-0701_articleMERS coronavirusneutralizing antibodiesSaudi ArabiaspikepseudotypingMERS-CoV
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Stefanie Gierer Heike Hofmann-Winkler Waleed H. Albuali Stephanie Bertram Abdullah M. Al-Rubaish Abdullah A. Yousef Awatif N. Al-Nafaie Amein K. Al-Ali Obeid E. Obeid Khaled R. Alkharsah Stefan Pöhlmann
spellingShingle	Stefanie Gierer Heike Hofmann-Winkler Waleed H. Albuali Stephanie Bertram Abdullah M. Al-Rubaish Abdullah A. Yousef Awatif N. Al-Nafaie Amein K. Al-Ali Obeid E. Obeid Khaled R. Alkharsah Stefan Pöhlmann Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia Emerging Infectious Diseases MERS coronavirus neutralizing antibodies Saudi Arabia spike pseudotyping MERS-CoV
author_facet	Stefanie Gierer Heike Hofmann-Winkler Waleed H. Albuali Stephanie Bertram Abdullah M. Al-Rubaish Abdullah A. Yousef Awatif N. Al-Nafaie Amein K. Al-Ali Obeid E. Obeid Khaled R. Alkharsah Stefan Pöhlmann
author_sort	Stefanie Gierer
title	Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_short	Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_full	Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_fullStr	Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_full_unstemmed	Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
title_sort	lack of mers coronavirus neutralizing antibodies in humans, eastern province, saudi arabia
publisher	Centers for Disease Control and Prevention
series	Emerging Infectious Diseases
issn	1080-6040 1080-6059
publishDate	2013-12-01
description	We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.
topic	MERS coronavirus neutralizing antibodies Saudi Arabia spike pseudotyping MERS-CoV
url	https://wwwnc.cdc.gov/eid/article/19/12/13-0701_article
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Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

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