Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia

Background: Frequency distribution of blood groups is important as it is used in modern medicine, genetic research, anthropology, and tracing ancestral relations of humans. The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered...

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Main Authors: Kassahun Tesfaye, Yohannes Petros, Mebeaselassie Andargie
Format: Article
Language:English
Published: SpringerOpen 2015-01-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
ABO
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863014000962
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spelling doaj-9cef54090f4e499784f98f62aa8a5ecd2020-11-25T02:29:51ZengSpringerOpenEgyptian Journal of Medical Human Genetics1110-86302015-01-01161717610.1016/j.ejmhg.2014.09.002Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, EthiopiaKassahun TesfayeYohannes PetrosMebeaselassie AndargieBackground: Frequency distribution of blood groups is important as it is used in modern medicine, genetic research, anthropology, and tracing ancestral relations of humans. The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. Aim of the study: To study and document the frequency of ABO and Rh (D) blood groups in three ethnic groups of Silte Zone, Ethiopia. Subjects and methods: ABO and Rh (D) typing was carried out during 2012 and a total of 441 students from both genders were randomly selected from Silte Secondary and Preparatory School, SNNPR, Ethiopia. Finger prick blood samples from both genders were tested for ABO and Rh (D) blood groups by the open slide test method. A drop of each of the antisera, anti-A, anti-B and anti-D was added and mixed with each blood sample and rocked gently for 60 s to observe agglutination. Results: The blood group “O” was predominant (36.73%, 40.14%, 46.26% in Sodo, Silte and Meskan ethnic groups, respectively) in all the Rh positive subjects whereas blood group “A” was predominant (5.4%) in the Rh negative subjects only in the Sodo ethnic group among the three ethnic groups. The percentage of Rh (D) positive and negative subjects was 91.16%, 93.19%, 91.84% and 8.84%, 6.81%, 8.16% in Sodo, Silte and Meskan ethnic groups, respectively. Conclusion: The frequency of ABO blood groups in both Rh positive and negative subjects among the three ethnic groups of the Silte Zone, Ethiopia was O > A > B > AB, except in the Sodo ethnic group where the blood group A was the commonest among Rh negative subjects.http://www.sciencedirect.com/science/article/pii/S1110863014000962ABOBlood groupsPopulation geneticsRh (D)
collection DOAJ
language English
format Article
sources DOAJ
author Kassahun Tesfaye
Yohannes Petros
Mebeaselassie Andargie
spellingShingle Kassahun Tesfaye
Yohannes Petros
Mebeaselassie Andargie
Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
Egyptian Journal of Medical Human Genetics
ABO
Blood groups
Population genetics
Rh (D)
author_facet Kassahun Tesfaye
Yohannes Petros
Mebeaselassie Andargie
author_sort Kassahun Tesfaye
title Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
title_short Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
title_full Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
title_fullStr Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
title_full_unstemmed Frequency distribution of ABO and Rh (D) blood group alleles in Silte Zone, Ethiopia
title_sort frequency distribution of abo and rh (d) blood group alleles in silte zone, ethiopia
publisher SpringerOpen
series Egyptian Journal of Medical Human Genetics
issn 1110-8630
publishDate 2015-01-01
description Background: Frequency distribution of blood groups is important as it is used in modern medicine, genetic research, anthropology, and tracing ancestral relations of humans. The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. Aim of the study: To study and document the frequency of ABO and Rh (D) blood groups in three ethnic groups of Silte Zone, Ethiopia. Subjects and methods: ABO and Rh (D) typing was carried out during 2012 and a total of 441 students from both genders were randomly selected from Silte Secondary and Preparatory School, SNNPR, Ethiopia. Finger prick blood samples from both genders were tested for ABO and Rh (D) blood groups by the open slide test method. A drop of each of the antisera, anti-A, anti-B and anti-D was added and mixed with each blood sample and rocked gently for 60 s to observe agglutination. Results: The blood group “O” was predominant (36.73%, 40.14%, 46.26% in Sodo, Silte and Meskan ethnic groups, respectively) in all the Rh positive subjects whereas blood group “A” was predominant (5.4%) in the Rh negative subjects only in the Sodo ethnic group among the three ethnic groups. The percentage of Rh (D) positive and negative subjects was 91.16%, 93.19%, 91.84% and 8.84%, 6.81%, 8.16% in Sodo, Silte and Meskan ethnic groups, respectively. Conclusion: The frequency of ABO blood groups in both Rh positive and negative subjects among the three ethnic groups of the Silte Zone, Ethiopia was O > A > B > AB, except in the Sodo ethnic group where the blood group A was the commonest among Rh negative subjects.
topic ABO
Blood groups
Population genetics
Rh (D)
url http://www.sciencedirect.com/science/article/pii/S1110863014000962
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