Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder
Abstract Background Little is known about opioid overdose or naloxone access among pregnant women. Objectives The objectives of this study were to determine the prevalence of non-fatal overdose, risk factors for overdose, and naloxone access among third trimester women in treatment for opioid use di...
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doaj-9d028ab5fa1048038ceb61860b2f7f7b2020-11-25T01:56:07ZengBMCAddiction Science & Clinical Practice1940-06402018-12-011311410.1186/s13722-018-0126-0Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorderSarah M. Bagley0Howard Cabral1Kelley Saia2Alyssa Brown3Christine Lloyd-Travaglini4Alexander Y. Walley5Ruth Rose-Jacobs6Department of Medicine, Boston University School of Medicine, Boston Medical CenterSchool of Public Health, Boston UniversityDepartment of Obstetrics and Gynecology, Boston University School of Medicine, Boston Medical CenterNortheastern University School of Public HealthSchool of Public Health, Boston UniversityDepartment of Medicine, Boston University School of Medicine, Boston Medical CenterDepartment of Pediatrics, Boston University School of Medicine, Boston Medical CenterAbstract Background Little is known about opioid overdose or naloxone access among pregnant women. Objectives The objectives of this study were to determine the prevalence of non-fatal overdose, risk factors for overdose, and naloxone access among third trimester women in treatment for opioid use disorder. Methods We collected baseline data from a case management parental-support intervention study. To explore the association of variables with past year overdose, we used Wilcoxon rank-sum test, Chi square or Fisher’s exact tests. Results Among 99 participants, 14% (95% CI 7–21%) reported past year overdose and 67% (95% CI 57–76%) had received overdose education and a naloxone kit. Younger age was the only variable associated with past year overdose. Conclusions In this sample, past year non-fatal overdose was common, younger age was a risk factor, and most participants had received a naloxone kit. Further work is needed to understand whether younger age is a risk factor in the general population of pregnant women with opioid use disorder and to identify other potential risk factors for overdose in this population.http://link.springer.com/article/10.1186/s13722-018-0126-0OpioidsOverdosePregnancyNaloxone |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sarah M. Bagley Howard Cabral Kelley Saia Alyssa Brown Christine Lloyd-Travaglini Alexander Y. Walley Ruth Rose-Jacobs |
spellingShingle |
Sarah M. Bagley Howard Cabral Kelley Saia Alyssa Brown Christine Lloyd-Travaglini Alexander Y. Walley Ruth Rose-Jacobs Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder Addiction Science & Clinical Practice Opioids Overdose Pregnancy Naloxone |
author_facet |
Sarah M. Bagley Howard Cabral Kelley Saia Alyssa Brown Christine Lloyd-Travaglini Alexander Y. Walley Ruth Rose-Jacobs |
author_sort |
Sarah M. Bagley |
title |
Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
title_short |
Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
title_full |
Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
title_fullStr |
Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
title_full_unstemmed |
Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
title_sort |
frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder |
publisher |
BMC |
series |
Addiction Science & Clinical Practice |
issn |
1940-0640 |
publishDate |
2018-12-01 |
description |
Abstract Background Little is known about opioid overdose or naloxone access among pregnant women. Objectives The objectives of this study were to determine the prevalence of non-fatal overdose, risk factors for overdose, and naloxone access among third trimester women in treatment for opioid use disorder. Methods We collected baseline data from a case management parental-support intervention study. To explore the association of variables with past year overdose, we used Wilcoxon rank-sum test, Chi square or Fisher’s exact tests. Results Among 99 participants, 14% (95% CI 7–21%) reported past year overdose and 67% (95% CI 57–76%) had received overdose education and a naloxone kit. Younger age was the only variable associated with past year overdose. Conclusions In this sample, past year non-fatal overdose was common, younger age was a risk factor, and most participants had received a naloxone kit. Further work is needed to understand whether younger age is a risk factor in the general population of pregnant women with opioid use disorder and to identify other potential risk factors for overdose in this population. |
topic |
Opioids Overdose Pregnancy Naloxone |
url |
http://link.springer.com/article/10.1186/s13722-018-0126-0 |
work_keys_str_mv |
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