Regulation of K<sup>+</sup> Conductance by a Hydrogen Bond in Kv2.1, Kv2.2, and Kv1.2 Channels

Regulation of K<sup>+</sup> Conductance by a Hydrogen Bond in Kv2.1, Kv2.2, and Kv1.2 Channels

The slow inactivation of voltage-gated potassium (Kv) channels plays an important role in controlling cellular excitability. Recently, the two hydrogen bonds (H-bonds) formed by W434-D447 and T439-Y445 have been reported to control the slow inactivation in <i>Shaker</i> potassium channel...

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Bibliographic Details
Main Authors: Yuchen Zhang, Xuefeng Zhang, Cuiyun Liu, Changlong Hu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Membranes
Subjects:
voltage-gated potassium channels
channel inactivation
hydrogen bonds
potassium conductance
Online Access:https://www.mdpi.com/2077-0375/11/3/190

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