Safety and efficacy of belimumab after B cell depletion therapy in systemic LUPUS erythematosus (BEAT-LUPUS) trial: statistical analysis plan

Safety and efficacy of belimumab after B cell depletion therapy in systemic LUPUS erythematosus (BEAT-LUPUS) trial: statistical analysis plan

Abstract Background There is limited evidence that rituximab, a B cell depletion therapy, is an effective treatment for systemic lupus erythematosus (SLE). Data on the mechanisms of B cell depletion in SLE indicate that the combination of rituximab and belimumab may be more effective than rituximab...

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Bibliographic Details
Main Authors: Patrick Muller, Kashfia Chowdhury, Caroline Gordon, Michael R. Ehrenstein, Caroline J. Doré
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Trials
Subjects:
Statistical analysis plan
Systemic lupus erythematosus
Rituximab
Belimumab
Anti-dsDNA
Flare
Online Access:http://link.springer.com/article/10.1186/s13063-020-04391-2

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http://link.springer.com/article/10.1186/s13063-020-04391-2

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