Application of Food-specific IgG Antibody Detection in Allergy Dermatosis

• Main Authors: Yine Hu, Shufang Dai, Bin Wang, Wei Qu, Aqeel Ashraf Muhammad, Junling Gao
• Format: Article
• Language: English
• Published: De Gruyter 2015-01-01
• Series: Open Medicine
• Subjects: food-specific IgG antibody; allergy dermatoses; food intolerance
• Online Access: http://www.degruyter.com/view/j/med.2015.10.issue-1/med-2015-0067/med-2015-0067.xml?format=INT

The application of food-specific IgG antibody detection in allergy dermatoses was explored. 181 patients with allergy dermatoses were diagnosed from January to September 2014 and 20 healthy subjects were selected. Fourteen kinds of food-specific IgG antibodies were detected by ELISA method among all the subjects. The positive rates of IgG antibody of the patient group and the healthy group were respectively 65.2% and 5.0%. The positive rates of IgG antibody of egg, milk, shrimp and crab took a large proportion in three groups of patients with three kinds of allergy dermatoses of urticaria, eczema and allergic dermatitis, the proportion of which was respectively 70.2%, 77.8% and 71.7%. Among urticaria and allergic dermatitis patients with positive antibody, the positive rate of children was significantly higher than that of adults (p<0.05) while there was no significant difference between children and adults among eczema patients with positive antibody (p>0.05). Allergy dermatoses are closely related to food-specific IgG antibodies, and the allergy dermatoses patients have a high incidence rate of food intolerance; detecting IgG antibody in the serum of patients is of great significance for the diagnosis and treatment of allergy dermatoses.