Benchtop Low-Frequency 60 MHz NMR Analysis of Urine: A Comparative Metabolomics Investigation

Benchtop Low-Frequency 60 MHz NMR Analysis of Urine: A Comparative Metabolomics Investigation

Metabolomics techniques are now applied in numerous fields, with the ability to provide information concerning a large number of metabolites from a single sample in a short timeframe. Although high-frequency (HF) nuclear magnetic resonance (NMR) analysis represents a common method of choice to perfo...

Full description

Bibliographic Details
Main Authors:	Justine Leenders, Martin Grootveld, Benita Percival, Miles Gibson, Federico Casanova, Philippe B. Wilson
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Metabolites
Subjects:	low-frequency NMR benchtop spectrometers type 2 diabetes metabolomics <sup>1</sup>H-<sup>1</sup>H COSY
Online Access:	https://www.mdpi.com/2218-1989/10/4/155

Similar Items

Structure Solution of Nano-Crystalline Small Molecules Using MicroED and Solid-State NMR Dipolar-Based Experiments
by: Nghia Tuan Duong, et al.
Published: (2021-07-01)

Solid State NMR for Nonexperts: An Overview of Simple but General Practical Methods
by: Ilya G. Shenderovich, et al.
Published: (2021-04-01)

NMR Crystallography at Fast Magic-Angle Spinning Frequencies: Application of Novel Recoupling Methods
by: Mukul G. Jain, et al.
Published: (2019-04-01)

<sup>1</sup>H-NMR Metabolomics Analysis of the Effect of Rubusoside on Serum Metabolites of Golden Hamsters on a High-Fat Diet
by: Li Li, et al.
Published: (2020-03-01)

A Comparative Study of Rat Urine <sup>1</sup>H-NMR Metabolome Changes Presumably Arising from Isoproterenol-Induced Heart Necrosis Versus Clarithromycin-Induced QT Interval Prolongation
by: Matthieu Dallons, et al.
Published: (2020-05-01)

An Untargeted Metabolomics Investigation of Milk from Dairy Cows with Clinical Mastitis by <sup>1</sup>H-NMR
by: Chenglin Zhu, et al.
Published: (2021-07-01)

Establishing a Metabolite Extraction Method to Study the Metabolome of <i>Blastocystis</i> Using NMR
by: Jamie M. Newton, et al.
Published: (2021-05-01)

Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms
by: Cécile Martias, et al.
Published: (2021-07-01)

Metabolite Profiles of Red and Yellow Watermelon (<i>Citrullus lanatus</i>) Cultivars Using a <sup>1</sup>H-NMR Metabolomics Approach
by: Fadzil Sulaiman, et al.
Published: (2020-07-01)

<sup>1</sup>H-NMR Metabolomics Analysis of the Effects of Sulfated Polysaccharides from Masson Pine Pollen in RAW264.7 Macrophage Cells
by: Fangchen Su, et al.
Published: (2019-05-01)

New Hybrid Tomato Cultivars: An NMR-Based Chemical Characterization
by: Cinzia Ingallina, et al.
Published: (2020-03-01)

Seeking a Fast Screening Method of the Varietal Origin of Olive Oil: The Usefulness of an NMR-Based Approach
by: Maria João Cabrita, et al.
Published: (2021-02-01)

NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells
by: Huang Youguo, et al.
Published: (2003-04-01)

Application of <sup>1</sup>H-NMR Metabolomics for the Discovery of Blood Plasma Biomarkers of a Mediterranean Diet
by: Shirin Macias, et al.
Published: (2019-09-01)

First Insights into the Urinary Metabolome of Captive Giraffes by Proton Nuclear Magnetic Resonance Spectroscopy
by: Chenglin Zhu, et al.
Published: (2020-04-01)

Untargeted Urinary <sup>1</sup>H NMR-Based Metabolomic Pattern as a Potential Platform in Breast Cancer Detection
by: Catarina L. Silva, et al.
Published: (2019-11-01)

NMR-Based Metabolomics in Metal-Based Drug Research
by: Federica De Castro, et al.
Published: (2019-06-01)

Current Methods of Magnetic Resonance for Noninvasive Assessment of Molecular Aspects of Pathoetiology in Multiple Sclerosis
by: Petra Hnilicová, et al.
Published: (2020-08-01)

Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants
by: Aline Mendes, et al.
Published: (2019-08-01)

Blueberry-Based Meals for Obese Patients with Metabolic Syndrome: A Multidisciplinary Metabolomic Pilot Study
by: Anatoly Petrovich Sobolev, et al.
Published: (2019-07-01)

Skeletal Muscle Metabolomic Responses to Endurance and Resistance Training in Rats under Chronic Unpredictable Mild Stress
by: Xiangyu Liu, et al.
Published: (2021-02-01)

Urinary <sup>1</sup>H-NMR Metabolic Signature in Subjects Undergoing Colonoscopy for Colon Cancer Diagnosis
by: Cristina Piras, et al.
Published: (2020-08-01)

Crystallographic and NMR Investigation of Ergometrine and Methylergometrine, Two Alkaloids from <i>Claviceps Purpurea</i>
by: Fiorella Meneghetti, et al.
Published: (2020-01-01)

Characteristic Metabolic Changes of the Crust from Dry-Aged Beef Using 2D NMR Spectroscopy
by: Hyun Cheol Kim, et al.
Published: (2020-07-01)

Identification of Metabolic Phenotypes in Young Adults with Obesity by <sup>1</sup>H NMR Metabolomics of Blood Serum
by: Khin Thandar Htun, et al.
Published: (2021-06-01)

Near UV-Vis and NMR Spectroscopic Methods for Rapid Screening of Antioxidant Molecules in Extra-Virgin Olive Oil
by: Giulia Vicario, et al.
Published: (2020-12-01)

Measuring Glycolytic Activity with Hyperpolarized [<sup>2</sup>H<sub>7</sub>, U-<sup>13</sup>C<sub>6</sub>] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions
by: Emmanuelle Flatt, et al.
Published: (2021-06-01)

Novel Nontoxic 5,9-Disubstituted SN38 Derivatives: Characterization of Their Pharmacological Properties and Interactions with DNA Oligomers
by: Elżbieta Bednarek, et al.
Published: (2021-07-01)

Structural Refinement of Carbimazole by NMR Crystallography
by: Andrea Scarperi, et al.
Published: (2021-07-01)

<sup>1</sup>H-NMR Profiling and Carbon Isotope Discrimination as Tools for the Comparative Assessment of Walnut (<i>Juglans regia</i> L.) Cultivars with Various Geographical and Genetic Origins—A Preliminary Study
by: Raluca Popescu, et al.
Published: (2019-04-01)

Metabolomics Reveals Discrimination of Chinese Propolis from Different Climatic Regions
by: Tongtong Wang, et al.
Published: (2020-04-01)

Role of Proton Motive Force in Photoinduction of Cytoplasmic Streaming in <i>Vallisneria</i> Mesophyll Cells
by: Akiko Harada, et al.
Published: (2020-03-01)

New Insights into the Structure-Function Relationship of the Endosomal-Type Na<sup>+</sup>, K<sup>+</sup>/H<sup>+</sup> Antiporter NHX6 from Mulberry (<i>Morus notabilis</i>)
by: Boning Cao, et al.
Published: (2020-01-01)

Genome-Wide Identification of Na<sup>+</sup>/H<sup>+</sup> Antiporter (NHX) Genes in Sugar Beet (<i>Beta vulgaris</i> L.) and Their Regulated Expression under Salt Stress
by: Guo-Qiang Wu, et al.
Published: (2019-05-01)

Investigation of Andrographolide Effect on Non-Infected Red Blood Cells Using the <sup>1</sup>H-NMR-Based Metabolomics Approach
by: Ashraf Ahmad Issa Alapid, et al.
Published: (2021-07-01)

Long-Term Isotope Records of Precipitation in Zagreb, Croatia
by: Ines Krajcar Bronić, et al.
Published: (2020-01-01)

Use of <sup>1</sup>H NMR to Detect the Percentage of Pure Fruit Juices in Blends
by: Lucia Marchetti, et al.
Published: (2019-07-01)

Description of AtCAX4 in Response to Abiotic Stress in Arabidopsis
by: Yuanyuan Bu, et al.
Published: (2021-01-01)

The Mode of SN38 Derivatives Interacting with Nicked DNA Mimics Biological Targeting of Topo I Poisons
by: Wojciech Bocian, et al.
Published: (2021-07-01)

Serum Metabolomics Profiling of Commercially Mixed Functional Foods—Effects in Beta-Amyloid Induced Rats Measured Using <sup>1</sup>H NMR Spectroscopy
by: Nur Hasnieza Mohd Rosli, et al.
Published: (2020-12-01)