SARS-CoV-2 infection and transmission in the North American deer mouse
Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2021-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23848-9 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
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DOAJ |
| author |
Bryan D. Griffin Mable Chan Nikesh Tailor Emelissa J. Mendoza Anders Leung Bryce M. Warner Ana T. Duggan Estella Moffat Shihua He Lauren Garnett Kaylie N. Tran Logan Banadyga Alixandra Albietz Kevin Tierney Jonathan Audet Alexander Bello Robert Vendramelli Amrit S. Boese Lisa Fernando L. Robbin Lindsay Claire M. Jardine Heidi Wood Guillaume Poliquin James E. Strong Michael Drebot David Safronetz Carissa Embury-Hyatt Darwyn Kobasa |
| spellingShingle |
Bryan D. Griffin Mable Chan Nikesh Tailor Emelissa J. Mendoza Anders Leung Bryce M. Warner Ana T. Duggan Estella Moffat Shihua He Lauren Garnett Kaylie N. Tran Logan Banadyga Alixandra Albietz Kevin Tierney Jonathan Audet Alexander Bello Robert Vendramelli Amrit S. Boese Lisa Fernando L. Robbin Lindsay Claire M. Jardine Heidi Wood Guillaume Poliquin James E. Strong Michael Drebot David Safronetz Carissa Embury-Hyatt Darwyn Kobasa SARS-CoV-2 infection and transmission in the North American deer mouse Nature Communications |
| author_facet |
Bryan D. Griffin Mable Chan Nikesh Tailor Emelissa J. Mendoza Anders Leung Bryce M. Warner Ana T. Duggan Estella Moffat Shihua He Lauren Garnett Kaylie N. Tran Logan Banadyga Alixandra Albietz Kevin Tierney Jonathan Audet Alexander Bello Robert Vendramelli Amrit S. Boese Lisa Fernando L. Robbin Lindsay Claire M. Jardine Heidi Wood Guillaume Poliquin James E. Strong Michael Drebot David Safronetz Carissa Embury-Hyatt Darwyn Kobasa |
| author_sort |
Bryan D. Griffin |
| title |
SARS-CoV-2 infection and transmission in the North American deer mouse |
| title_short |
SARS-CoV-2 infection and transmission in the North American deer mouse |
| title_full |
SARS-CoV-2 infection and transmission in the North American deer mouse |
| title_fullStr |
SARS-CoV-2 infection and transmission in the North American deer mouse |
| title_full_unstemmed |
SARS-CoV-2 infection and transmission in the North American deer mouse |
| title_sort |
sars-cov-2 infection and transmission in the north american deer mouse |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2021-06-01 |
| description |
Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit SARS-CoV-2 to naïve deer mice. |
| url |
https://doi.org/10.1038/s41467-021-23848-9 |
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doaj-9da1c4d9e45e4f76a8779fa6d68d2b3b2021-06-20T11:13:06ZengNature Publishing GroupNature Communications2041-17232021-06-0112111010.1038/s41467-021-23848-9SARS-CoV-2 infection and transmission in the North American deer mouseBryan D. Griffin0Mable Chan1Nikesh Tailor2Emelissa J. Mendoza3Anders Leung4Bryce M. Warner5Ana T. Duggan6Estella Moffat7Shihua He8Lauren Garnett9Kaylie N. Tran10Logan Banadyga11Alixandra Albietz12Kevin Tierney13Jonathan Audet14Alexander Bello15Robert Vendramelli16Amrit S. Boese17Lisa Fernando18L. Robbin Lindsay19Claire M. Jardine20Heidi Wood21Guillaume Poliquin22James E. Strong23Michael Drebot24David Safronetz25Carissa Embury-Hyatt26Darwyn Kobasa27Zoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaScience Technology Cores and Services, National Microbiology Laboratory, Public Health Agency of CanadaNational Centre for Foreign Animal Disease, Canadian Food Inspection AgencyZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaDepartment of Pathobiology, Canadian Wildlife Health Cooperative, Department of Pathobiology, University of GuelphZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaDepartment of Medical Microbiology and Infectious Diseases, College of Medicine, Faculty of Health Sciences, University of ManitobaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaNational Centre for Foreign Animal Disease, Canadian Food Inspection AgencyZoonotic Diseases and Special Pathogens Division, National Microbiology Laboratory, Public Health Agency of CanadaDeer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illness. Additionally, infected deer mice can transmit SARS-CoV-2 to naïve deer mice.https://doi.org/10.1038/s41467-021-23848-9 |