Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus

Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus

Neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) is a life-threatening disorder and early diagnosis and proper treatment are critical in the management of this neuropsychiatric manifestations in lupus. Brain magnetic resonance imaging (MRI), electroencephalogram (EEG), neuropsychol...

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Main Authors: Hiroshi Okamoto, Akiko Kobayashi, Hisashi Yamanaka
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/268436
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spelling doaj-9dce81a5a874453189f5f8495714f8f42020-11-24T21:26:39ZengHindawi LimitedJournal of Biomedicine and Biotechnology1110-72431110-72512010-01-01201010.1155/2010/268436268436Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus ErythematosusHiroshi Okamoto0Akiko Kobayashi1Hisashi Yamanaka2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo 162-0054, JapanInstitute of Rheumatology, Tokyo Women’s Medical University, Tokyo 162-0054, JapanInstitute of Rheumatology, Tokyo Women’s Medical University, Tokyo 162-0054, JapanNeuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) is a life-threatening disorder and early diagnosis and proper treatment are critical in the management of this neuropsychiatric manifestations in lupus. Brain magnetic resonance imaging (MRI), electroencephalogram (EEG), neuropsychological tests, and lumbar puncture are clinical used for the diagnosis of NPSLE. In addition to these tests, cytokine and chemokine levels in CSF have been reported as useful diagnostic marker of NPSLE. Based on the number of recently published studies, this review overviewed the roles of cytokines and chemokines in NPSLE.http://dx.doi.org/10.1155/2010/268436
collection DOAJ
language English
format Article
sources DOAJ
author Hiroshi Okamoto
Akiko Kobayashi
Hisashi Yamanaka
spellingShingle Hiroshi Okamoto
Akiko Kobayashi
Hisashi Yamanaka
Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
Journal of Biomedicine and Biotechnology
author_facet Hiroshi Okamoto
Akiko Kobayashi
Hisashi Yamanaka
author_sort Hiroshi Okamoto
title Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
title_short Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
title_full Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
title_fullStr Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
title_full_unstemmed Cytokines and Chemokines in Neuropsychiatric Syndromes of Systemic Lupus Erythematosus
title_sort cytokines and chemokines in neuropsychiatric syndromes of systemic lupus erythematosus
publisher Hindawi Limited
series Journal of Biomedicine and Biotechnology
issn 1110-7243
1110-7251
publishDate 2010-01-01
description Neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE) is a life-threatening disorder and early diagnosis and proper treatment are critical in the management of this neuropsychiatric manifestations in lupus. Brain magnetic resonance imaging (MRI), electroencephalogram (EEG), neuropsychological tests, and lumbar puncture are clinical used for the diagnosis of NPSLE. In addition to these tests, cytokine and chemokine levels in CSF have been reported as useful diagnostic marker of NPSLE. Based on the number of recently published studies, this review overviewed the roles of cytokines and chemokines in NPSLE.
url http://dx.doi.org/10.1155/2010/268436
work_keys_str_mv AT hiroshiokamoto cytokinesandchemokinesinneuropsychiatricsyndromesofsystemiclupuserythematosus
AT akikokobayashi cytokinesandchemokinesinneuropsychiatricsyndromesofsystemiclupuserythematosus
AT hisashiyamanaka cytokinesandchemokinesinneuropsychiatricsyndromesofsystemiclupuserythematosus
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