The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure

Objectives: To evaluate the short-term intraocular pressure (IOP) changes after intravitreal injection of 0.05 mL (1.25 mg) bevacizumab. Materials and Methods: The study included 57 eyes of 57 patients who had an intravitreal injection of 0.05 mL bevacizumab. The IOPs (measured by TonoPen) before...

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Main Authors: Şehnaz Özçalışkan, Pelin Yılmazbaş, Faruk Öztürk, Özlem Beyazyıldız
Format: Article
Language:English
Published: Galenos Yayinevi 2014-10-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/article_7375/The-Short-term-Effect-Of-Intravitreal-Bevacizumab-Injection-On-Intraocular-Pressure
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spelling doaj-9de7b52edf1143909dc1019f974012e72020-11-24T23:29:21ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612014-10-0144536136410.4274/tjo.26122The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular PressureŞehnaz Özçalışkan0Pelin Yılmazbaş1 Faruk Öztürk2Özlem Beyazyıldız3Van Başkale Devlet Hastanesi, Göz Hastalıkları Kliniği, Van, TürkiyeUlucanlar Göz Eğitim ve Araştırma Hastanesi, Ankara, TürkiyeYıldırım Beyazıt Üniversitesi Atatürk Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Anabilim Dalı, Ankara, TürkiyeSamsun Kadın Doğum ve Çocuk Hastalıkları Hastanesi, Göz Hastalıkları Kliniği, Samsun, TürkiyeObjectives: To evaluate the short-term intraocular pressure (IOP) changes after intravitreal injection of 0.05 mL (1.25 mg) bevacizumab. Materials and Methods: The study included 57 eyes of 57 patients who had an intravitreal injection of 0.05 mL bevacizumab. The IOPs (measured by TonoPen) before the injection and one minute, 30 minutes, and one hour after the injection were recorded. The changes in IOP in time were evaluated by using the SPSS 15.0 programme. Results: The mean age of the patients was 62.8±11 years. The patients who received an 0.05 mL bevacizumab injection had diagnosis of diabetic retinopathy (36 eyes), retinal vein occlusion (10 eyes), exudative age-related macular degeneration (7 eyes), and chronic central serous retinopathy (4 eyes). Mean IOP was 17.91±3.7 mmHg before the injection. Mean IOP was 34.58±13.5 mmHg on first minute, 21.86±5.39 mmHg on 30 minutes, and 20.64±5.77 mm Hg one hour after the injection. The difference between the pre-injection IOPs and post-injection IOPs in different time periods was statistically significant (p<0.05). Conclusion: After intravitreal injection of 0.05 mL of bevacizumab, an acute and transient rise in IOP developed immediately. IOP normalizes without any medical or surgical treatment in short term. (Turk J Ophthalmol 2014; 44: 361-4)http://www.oftalmoloji.org/article_7375/The-Short-term-Effect-Of-Intravitreal-Bevacizumab-Injection-On-Intraocular-PressureBevacizumabintraocular pressureintravitreal injection
collection DOAJ
language English
format Article
sources DOAJ
author Şehnaz Özçalışkan
Pelin Yılmazbaş
Faruk Öztürk
Özlem Beyazyıldız
spellingShingle Şehnaz Özçalışkan
Pelin Yılmazbaş
Faruk Öztürk
Özlem Beyazyıldız
The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
Türk Oftalmoloji Dergisi
Bevacizumab
intraocular pressure
intravitreal injection
author_facet Şehnaz Özçalışkan
Pelin Yılmazbaş
Faruk Öztürk
Özlem Beyazyıldız
author_sort Şehnaz Özçalışkan
title The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
title_short The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
title_full The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
title_fullStr The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
title_full_unstemmed The Short-Term Effect of Intravitreal Bevacizumab Injection on Intraocular Pressure
title_sort short-term effect of intravitreal bevacizumab injection on intraocular pressure
publisher Galenos Yayinevi
series Türk Oftalmoloji Dergisi
issn 1300-0659
2147-2661
publishDate 2014-10-01
description Objectives: To evaluate the short-term intraocular pressure (IOP) changes after intravitreal injection of 0.05 mL (1.25 mg) bevacizumab. Materials and Methods: The study included 57 eyes of 57 patients who had an intravitreal injection of 0.05 mL bevacizumab. The IOPs (measured by TonoPen) before the injection and one minute, 30 minutes, and one hour after the injection were recorded. The changes in IOP in time were evaluated by using the SPSS 15.0 programme. Results: The mean age of the patients was 62.8±11 years. The patients who received an 0.05 mL bevacizumab injection had diagnosis of diabetic retinopathy (36 eyes), retinal vein occlusion (10 eyes), exudative age-related macular degeneration (7 eyes), and chronic central serous retinopathy (4 eyes). Mean IOP was 17.91±3.7 mmHg before the injection. Mean IOP was 34.58±13.5 mmHg on first minute, 21.86±5.39 mmHg on 30 minutes, and 20.64±5.77 mm Hg one hour after the injection. The difference between the pre-injection IOPs and post-injection IOPs in different time periods was statistically significant (p<0.05). Conclusion: After intravitreal injection of 0.05 mL of bevacizumab, an acute and transient rise in IOP developed immediately. IOP normalizes without any medical or surgical treatment in short term. (Turk J Ophthalmol 2014; 44: 361-4)
topic Bevacizumab
intraocular pressure
intravitreal injection
url http://www.oftalmoloji.org/article_7375/The-Short-term-Effect-Of-Intravitreal-Bevacizumab-Injection-On-Intraocular-Pressure
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