Bioprinting of skin constructs for wound healing
Abstract Extensive burns and full-thickness skin wounds are difficult to repair. Autologous split-thickness skin graft (ASSG) is still used as the gold standard in the clinic. However, the shortage of donor skin tissues is a serious problem. A potential solution to this problem is to fabricate skin...
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Oxford University Press
2018-01-01
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doaj-9deacc8e21564c4d8b5420f15e19c4312020-11-25T03:46:09ZengOxford University PressBurns & Trauma2321-38762018-01-016111010.1186/s41038-017-0104-xBioprinting of skin constructs for wound healingPeng He0Junning Zhao1Jiumeng Zhang2Bo Li3Zhiyuan Gou4Maling Gou5Xiaolu Li6The Affiliated Hospital of Southwest Medical University, the department of Plastic & Burns SurgerySichuan Academy of Chinese Medical Sciences, Sichuan Translational Medicine Center of Chinese MedicineState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan UniversityState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan UniversityState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan UniversityState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan UniversityThe Affiliated Hospital of Southwest Medical University, the department of Plastic & Burns SurgeryAbstract Extensive burns and full-thickness skin wounds are difficult to repair. Autologous split-thickness skin graft (ASSG) is still used as the gold standard in the clinic. However, the shortage of donor skin tissues is a serious problem. A potential solution to this problem is to fabricate skin constructs using biomaterial scaffolds with or without cells. Bioprinting is being applied to address the need for skin tissues suitable for transplantation, and can lead to the development of skin equivalents for wound healing therapy. Here, we summarize strategies of bioprinting and review current advances of bioprinting of skin constructs. There will be challenges on the way of 3D bioprinting for skin regeneration, but we still believe bioprinting will be potential skills for wounds healing in the foreseeable future.http://link.springer.com/article/10.1186/s41038-017-0104-xBioprintingSkin constructsWound healingBioink |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Peng He Junning Zhao Jiumeng Zhang Bo Li Zhiyuan Gou Maling Gou Xiaolu Li |
spellingShingle |
Peng He Junning Zhao Jiumeng Zhang Bo Li Zhiyuan Gou Maling Gou Xiaolu Li Bioprinting of skin constructs for wound healing Burns & Trauma Bioprinting Skin constructs Wound healing Bioink |
author_facet |
Peng He Junning Zhao Jiumeng Zhang Bo Li Zhiyuan Gou Maling Gou Xiaolu Li |
author_sort |
Peng He |
title |
Bioprinting of skin constructs for wound healing |
title_short |
Bioprinting of skin constructs for wound healing |
title_full |
Bioprinting of skin constructs for wound healing |
title_fullStr |
Bioprinting of skin constructs for wound healing |
title_full_unstemmed |
Bioprinting of skin constructs for wound healing |
title_sort |
bioprinting of skin constructs for wound healing |
publisher |
Oxford University Press |
series |
Burns & Trauma |
issn |
2321-3876 |
publishDate |
2018-01-01 |
description |
Abstract Extensive burns and full-thickness skin wounds are difficult to repair. Autologous split-thickness skin graft (ASSG) is still used as the gold standard in the clinic. However, the shortage of donor skin tissues is a serious problem. A potential solution to this problem is to fabricate skin constructs using biomaterial scaffolds with or without cells. Bioprinting is being applied to address the need for skin tissues suitable for transplantation, and can lead to the development of skin equivalents for wound healing therapy. Here, we summarize strategies of bioprinting and review current advances of bioprinting of skin constructs. There will be challenges on the way of 3D bioprinting for skin regeneration, but we still believe bioprinting will be potential skills for wounds healing in the foreseeable future. |
topic |
Bioprinting Skin constructs Wound healing Bioink |
url |
http://link.springer.com/article/10.1186/s41038-017-0104-x |
work_keys_str_mv |
AT penghe bioprintingofskinconstructsforwoundhealing AT junningzhao bioprintingofskinconstructsforwoundhealing AT jiumengzhang bioprintingofskinconstructsforwoundhealing AT boli bioprintingofskinconstructsforwoundhealing AT zhiyuangou bioprintingofskinconstructsforwoundhealing AT malinggou bioprintingofskinconstructsforwoundhealing AT xiaoluli bioprintingofskinconstructsforwoundhealing |
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1724507532920094720 |