DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites.

DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites.

Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction sites, modern virtual screening tools developed for optimal performance agains...

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Bibliographic Details
Main Authors: Ragul Gowthaman, Sergey Lyskov, John Karanicolas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4504481?pdf=render

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