Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains
The aim of the present work was to study parasitological, molecular, and genetic aspects in descendants of crossbreedings between a totally resistant Biomphalaria tenagophila strain (Taim, RS) and another one highly susceptible (Joinville, SC) to Schistosoma mansoni. Descendants F1 and F2 were submi...
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Instituto Oswaldo Cruz, Ministério da Saúde
2005-02-01
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doaj-9e1742cff9c74640bd18e96f6a3368202020-11-25T02:27:13ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80602005-02-011001192310.1590/S0074-02762005000100004Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strainsFlorence Mara RosaAna Lúcia Brunialti GodardVasco AzevedoPaulo Marcos Zech CoelhoThe aim of the present work was to study parasitological, molecular, and genetic aspects in descendants of crossbreedings between a totally resistant Biomphalaria tenagophila strain (Taim, RS) and another one highly susceptible (Joinville, SC) to Schistosoma mansoni. Descendants F1 and F2 were submitted to S. mansoni infection (LE strain). The susceptibility rates for individuals from Group F1 were 0 to 0.6%, and from Group F2 was 7.2%. The susceptible individuals from Group F2 discharged a lower number of cercariae, when compared with the susceptible parental group, and in 2 out of 9 positive snails the cercarial elimination was discontinued. In order to identify genetic markers associated with resistance the genotype of parental snails and their offspring F1 and F2 were analyzed by means of the randomly amplified polymorphic DNA method. Nevertheless, it was not possible to detect any marker associated to resistance, but the results showed that in the mentioned species the resistance character is determined by two dominant genes.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000100004Biomphalaria tenagophiladominant resistance characterSchistosoma mansonicrossbreedings |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Florence Mara Rosa Ana Lúcia Brunialti Godard Vasco Azevedo Paulo Marcos Zech Coelho |
spellingShingle |
Florence Mara Rosa Ana Lúcia Brunialti Godard Vasco Azevedo Paulo Marcos Zech Coelho Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains Memórias do Instituto Oswaldo Cruz. Biomphalaria tenagophila dominant resistance character Schistosoma mansoni crossbreedings |
author_facet |
Florence Mara Rosa Ana Lúcia Brunialti Godard Vasco Azevedo Paulo Marcos Zech Coelho |
author_sort |
Florence Mara Rosa |
title |
Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains |
title_short |
Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains |
title_full |
Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains |
title_fullStr |
Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains |
title_full_unstemmed |
Biomphalaria tenagophila: dominant character of the resistance to Schistosoma mansoni in descendants of crossbreedings between resistant (Taim, RS) and susceptible (Joinville, SC) strains |
title_sort |
biomphalaria tenagophila: dominant character of the resistance to schistosoma mansoni in descendants of crossbreedings between resistant (taim, rs) and susceptible (joinville, sc) strains |
publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
series |
Memórias do Instituto Oswaldo Cruz. |
issn |
0074-0276 1678-8060 |
publishDate |
2005-02-01 |
description |
The aim of the present work was to study parasitological, molecular, and genetic aspects in descendants of crossbreedings between a totally resistant Biomphalaria tenagophila strain (Taim, RS) and another one highly susceptible (Joinville, SC) to Schistosoma mansoni. Descendants F1 and F2 were submitted to S. mansoni infection (LE strain). The susceptibility rates for individuals from Group F1 were 0 to 0.6%, and from Group F2 was 7.2%. The susceptible individuals from Group F2 discharged a lower number of cercariae, when compared with the susceptible parental group, and in 2 out of 9 positive snails the cercarial elimination was discontinued. In order to identify genetic markers associated with resistance the genotype of parental snails and their offspring F1 and F2 were analyzed by means of the randomly amplified polymorphic DNA method. Nevertheless, it was not possible to detect any marker associated to resistance, but the results showed that in the mentioned species the resistance character is determined by two dominant genes. |
topic |
Biomphalaria tenagophila dominant resistance character Schistosoma mansoni crossbreedings |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000100004 |
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