Type III collagen disorders: A case report and review of literature
Collagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in suben...
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doaj-9e2c5899356d4e4dbd770ddc984f34912020-11-24T21:25:13ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292016-01-01591757710.4103/0377-4929.174822Type III collagen disorders: A case report and review of literatureA AnithaMahesha VankalakuntiVishwanath SiddiniKishore BabuRavishankar BonuSudarshan BallalCollagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in subendothelium and mesangium in CG, they are found only in the basement membrane in NPS. The clinical features of CG are confined to the kidney, NPS has associated extra-renal manifestations. Electron microscopy is essential to make the renal diagnosis in both these rare diseases. Both the entities considered to be systemic diseases evidence to suggest similar deposition in other organs, understanding etiopathogenesis and disease progression await research.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=75;epage=77;aulast=AnithaCollagen type IIIcollagenofibrotic glomerulopathyelectron microscopynail patella syndromerenal replacement therapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
A Anitha Mahesha Vankalakunti Vishwanath Siddini Kishore Babu Ravishankar Bonu Sudarshan Ballal |
spellingShingle |
A Anitha Mahesha Vankalakunti Vishwanath Siddini Kishore Babu Ravishankar Bonu Sudarshan Ballal Type III collagen disorders: A case report and review of literature Indian Journal of Pathology and Microbiology Collagen type III collagenofibrotic glomerulopathy electron microscopy nail patella syndrome renal replacement therapy |
author_facet |
A Anitha Mahesha Vankalakunti Vishwanath Siddini Kishore Babu Ravishankar Bonu Sudarshan Ballal |
author_sort |
A Anitha |
title |
Type III collagen disorders: A case report and review of literature |
title_short |
Type III collagen disorders: A case report and review of literature |
title_full |
Type III collagen disorders: A case report and review of literature |
title_fullStr |
Type III collagen disorders: A case report and review of literature |
title_full_unstemmed |
Type III collagen disorders: A case report and review of literature |
title_sort |
type iii collagen disorders: a case report and review of literature |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Pathology and Microbiology |
issn |
0377-4929 |
publishDate |
2016-01-01 |
description |
Collagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in subendothelium and mesangium in CG, they are found only in the basement membrane in NPS. The clinical features of CG are confined to the kidney, NPS has associated extra-renal manifestations. Electron microscopy is essential to make the renal diagnosis in both these rare diseases. Both the entities considered to be systemic diseases evidence to suggest similar deposition in other organs, understanding etiopathogenesis and disease progression await research. |
topic |
Collagen type III collagenofibrotic glomerulopathy electron microscopy nail patella syndrome renal replacement therapy |
url |
http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=75;epage=77;aulast=Anitha |
work_keys_str_mv |
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1725984004728946688 |