Type III collagen disorders: A case report and review of literature

Collagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in suben...

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Main Authors: A Anitha, Mahesha Vankalakunti, Vishwanath Siddini, Kishore Babu, Ravishankar Bonu, Sudarshan Ballal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=75;epage=77;aulast=Anitha
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spelling doaj-9e2c5899356d4e4dbd770ddc984f34912020-11-24T21:25:13ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292016-01-01591757710.4103/0377-4929.174822Type III collagen disorders: A case report and review of literatureA AnithaMahesha VankalakuntiVishwanath SiddiniKishore BabuRavishankar BonuSudarshan BallalCollagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in subendothelium and mesangium in CG, they are found only in the basement membrane in NPS. The clinical features of CG are confined to the kidney, NPS has associated extra-renal manifestations. Electron microscopy is essential to make the renal diagnosis in both these rare diseases. Both the entities considered to be systemic diseases evidence to suggest similar deposition in other organs, understanding etiopathogenesis and disease progression await research.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=75;epage=77;aulast=AnithaCollagen type IIIcollagenofibrotic glomerulopathyelectron microscopynail patella syndromerenal replacement therapy
collection DOAJ
language English
format Article
sources DOAJ
author A Anitha
Mahesha Vankalakunti
Vishwanath Siddini
Kishore Babu
Ravishankar Bonu
Sudarshan Ballal
spellingShingle A Anitha
Mahesha Vankalakunti
Vishwanath Siddini
Kishore Babu
Ravishankar Bonu
Sudarshan Ballal
Type III collagen disorders: A case report and review of literature
Indian Journal of Pathology and Microbiology
Collagen type III
collagenofibrotic glomerulopathy
electron microscopy
nail patella syndrome
renal replacement therapy
author_facet A Anitha
Mahesha Vankalakunti
Vishwanath Siddini
Kishore Babu
Ravishankar Bonu
Sudarshan Ballal
author_sort A Anitha
title Type III collagen disorders: A case report and review of literature
title_short Type III collagen disorders: A case report and review of literature
title_full Type III collagen disorders: A case report and review of literature
title_fullStr Type III collagen disorders: A case report and review of literature
title_full_unstemmed Type III collagen disorders: A case report and review of literature
title_sort type iii collagen disorders: a case report and review of literature
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Pathology and Microbiology
issn 0377-4929
publishDate 2016-01-01
description Collagen type III is a normal component of interstitium and blood vessels. Collagenofibrotic glomerulopathy (CG) and nail patella syndrome (NPS) are the diseases of abnormal type III collagen deposition. In spite of these curved frayed structures with a periodicity of 45-60 nm are deposited in subendothelium and mesangium in CG, they are found only in the basement membrane in NPS. The clinical features of CG are confined to the kidney, NPS has associated extra-renal manifestations. Electron microscopy is essential to make the renal diagnosis in both these rare diseases. Both the entities considered to be systemic diseases evidence to suggest similar deposition in other organs, understanding etiopathogenesis and disease progression await research.
topic Collagen type III
collagenofibrotic glomerulopathy
electron microscopy
nail patella syndrome
renal replacement therapy
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=75;epage=77;aulast=Anitha
work_keys_str_mv AT aanitha typeiiicollagendisordersacasereportandreviewofliterature
AT maheshavankalakunti typeiiicollagendisordersacasereportandreviewofliterature
AT vishwanathsiddini typeiiicollagendisordersacasereportandreviewofliterature
AT kishorebabu typeiiicollagendisordersacasereportandreviewofliterature
AT ravishankarbonu typeiiicollagendisordersacasereportandreviewofliterature
AT sudarshanballal typeiiicollagendisordersacasereportandreviewofliterature
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