Bioinformatics insights into acute lung injury/acute respiratory distress syndrome
Abstract Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity an...
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Online Access: | https://doi.org/10.1186/2001-1326-1-9 |
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doaj-9e31c5a7049f4f4f9ce694270465044a2020-11-25T02:50:37ZengWileyClinical and Translational Medicine2001-13262012-12-0111n/an/a10.1186/2001-1326-1-9Bioinformatics insights into acute lung injury/acute respiratory distress syndromeXiaocong Fang0Chunxue Bai1Xiangdong Wang2Department of Pulmonary MedicineZhongshan HospitalFudan UniversityShanghaiChinaDepartment of Pulmonary MedicineZhongshan HospitalFudan UniversityShanghaiChinaDepartment of Pulmonary MedicineZhongshan HospitalFudan UniversityShanghaiChinaAbstract Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment.https://doi.org/10.1186/2001-1326-1-9Acute lung injuryAcute respiratory distress syndromeGenomicsProteomicsMetabolomicsBioinformatics |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xiaocong Fang Chunxue Bai Xiangdong Wang |
spellingShingle |
Xiaocong Fang Chunxue Bai Xiangdong Wang Bioinformatics insights into acute lung injury/acute respiratory distress syndrome Clinical and Translational Medicine Acute lung injury Acute respiratory distress syndrome Genomics Proteomics Metabolomics Bioinformatics |
author_facet |
Xiaocong Fang Chunxue Bai Xiangdong Wang |
author_sort |
Xiaocong Fang |
title |
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_short |
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_full |
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_fullStr |
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_full_unstemmed |
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
title_sort |
bioinformatics insights into acute lung injury/acute respiratory distress syndrome |
publisher |
Wiley |
series |
Clinical and Translational Medicine |
issn |
2001-1326 |
publishDate |
2012-12-01 |
description |
Abstract Bioinformatics is the application of omics science, information technology, mathematics and statistics in the field of biomarker detection. Clinical bioinformatics can be applied for identification and validation of new biomarkers to improve current methods of monitoring disease activity and identify new therapeutic targets. Acute lung injurt (ALI)/Acute respiratory distress syndrome (ARDS) affects a large number of patients with a poor prognosis. The present review mainly focused on the progress in understanding disease heterogeneity through the use of evolving biological, genomic, and genetic approaches and the role of clinical bioinformatics in the pathogenesis and treatment of ALI/ARDS. The remarkable advances in clinical bioinformatics can be a new way for understanding disease pathogenesis, diagnosis and treatment. |
topic |
Acute lung injury Acute respiratory distress syndrome Genomics Proteomics Metabolomics Bioinformatics |
url |
https://doi.org/10.1186/2001-1326-1-9 |
work_keys_str_mv |
AT xiaocongfang bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome AT chunxuebai bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome AT xiangdongwang bioinformaticsinsightsintoacutelunginjuryacuterespiratorydistresssyndrome |
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1724737530661699584 |