Intestinal stenosis in Crohn’s disease shows a generalized upregulation of genes involved in collagen metabolism and recognition that could serve as novel anti-fibrotic drug targets
Background and Aims: Crohn’s disease (CD) can be complicated by intestinal fibrosis. Pharmacological therapies against intestinal fibrosis are not available. The aim of this study was to determine whether pathways involved in collagen metabolism are upregulated in intestinal fibrosis, and to discuss...
Main Authors: | Wouter Tobias van Haaften, Tjasso Blokzijl, Hendrik Sijbrand Hofker, Peter Olinga, Gerard Dijkstra, Ruud A. Bank, Miriam Boersema |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-08-01
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Series: | Therapeutic Advances in Gastroenterology |
Online Access: | https://doi.org/10.1177/1756284820952578 |
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