Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden
By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed sampl...
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| Language: | English |
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Centers for Disease Control and Prevention
2018-10-01
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| Series: | Emerging Infectious Diseases |
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| Online Access: | https://wwwnc.cdc.gov/eid/article/24/10/17-1842_article |
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doaj-9e516f7f0b814b8c93d3bfb45b3bbac62020-11-24T21:50:29ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-10-0124101874188110.3201/eid2410.171842Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, SwedenJohan KaarmeHilde RiedelWesley SchaalHong YinTryggve NevéusÅsa MelhusBy collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non–ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.https://wwwnc.cdc.gov/eid/article/24/10/17-1842_articlecarriage ratesEnterobacteriaceaebacteriaextended-spectrum β-lactamasesESBLshealthy preschool children |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus |
| spellingShingle |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden Emerging Infectious Diseases carriage rates Enterobacteriaceae bacteria extended-spectrum β-lactamases ESBLs healthy preschool children |
| author_facet |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus |
| author_sort |
Johan Kaarme |
| title |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
| title_short |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
| title_full |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
| title_fullStr |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
| title_full_unstemmed |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
| title_sort |
rapid increase in carriage rates of enterobacteriaceae producing extended-spectrum β-lactamases in healthy preschool children, sweden |
| publisher |
Centers for Disease Control and Prevention |
| series |
Emerging Infectious Diseases |
| issn |
1080-6040 1080-6059 |
| publishDate |
2018-10-01 |
| description |
By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non–ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden. |
| topic |
carriage rates Enterobacteriaceae bacteria extended-spectrum β-lactamases ESBLs healthy preschool children |
| url |
https://wwwnc.cdc.gov/eid/article/24/10/17-1842_article |
| work_keys_str_mv |
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