Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden
By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed sampl...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Centers for Disease Control and Prevention
2018-10-01
|
Series: | Emerging Infectious Diseases |
Subjects: | |
Online Access: | https://wwwnc.cdc.gov/eid/article/24/10/17-1842_article |
id |
doaj-9e516f7f0b814b8c93d3bfb45b3bbac6 |
---|---|
record_format |
Article |
spelling |
doaj-9e516f7f0b814b8c93d3bfb45b3bbac62020-11-24T21:50:29ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-10-0124101874188110.3201/eid2410.171842Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, SwedenJohan KaarmeHilde RiedelWesley SchaalHong YinTryggve NevéusÅsa MelhusBy collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non–ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden.https://wwwnc.cdc.gov/eid/article/24/10/17-1842_articlecarriage ratesEnterobacteriaceaebacteriaextended-spectrum β-lactamasesESBLshealthy preschool children |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus |
spellingShingle |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden Emerging Infectious Diseases carriage rates Enterobacteriaceae bacteria extended-spectrum β-lactamases ESBLs healthy preschool children |
author_facet |
Johan Kaarme Hilde Riedel Wesley Schaal Hong Yin Tryggve Nevéus Åsa Melhus |
author_sort |
Johan Kaarme |
title |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
title_short |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
title_full |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
title_fullStr |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
title_full_unstemmed |
Rapid Increase in Carriage Rates of Enterobacteriaceae Producing Extended-Spectrum β-Lactamases in Healthy Preschool Children, Sweden |
title_sort |
rapid increase in carriage rates of enterobacteriaceae producing extended-spectrum β-lactamases in healthy preschool children, sweden |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2018-10-01 |
description |
By collecting and analyzing diapers, we identified a >6-fold increase in carriage of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae for healthy preschool children in Sweden (p<0.0001). For 6 of the 50 participating preschools, the carriage rate was >40%. We analyzed samples from 334 children and found 56 containing >1 ESBL producer. The prevalence in the study population increased from 2.6% in 2010 to 16.8% in 2016 (p<0.0001), and for 6 of the 50 participating preschools, the carriage rate was >40%. Furthermore, 58% of the ESBL producers were multidrug resistant, and transmission of ESBL-producing and non–ESBL-producing strains was observed at several of the preschools. Toddlers appear to be major carriers of ESBL producers in Sweden. |
topic |
carriage rates Enterobacteriaceae bacteria extended-spectrum β-lactamases ESBLs healthy preschool children |
url |
https://wwwnc.cdc.gov/eid/article/24/10/17-1842_article |
work_keys_str_mv |
AT johankaarme rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden AT hilderiedel rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden AT wesleyschaal rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden AT hongyin rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden AT tryggveneveus rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden AT asamelhus rapidincreaseincarriageratesofenterobacteriaceaeproducingextendedspectrumblactamasesinhealthypreschoolchildrensweden |
_version_ |
1725883580950773760 |