Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development.
Serotonin and its receptors (HTRs) play critical roles in brain development and in the regulation of cognition, mood, and anxiety. HTRs are highly expressed in human prefrontal cortex and exert control over prefrontal excitability. The serotonin system is a key treatment target for several psychiatr...
Main Authors: | Evelyn K Lambe, Stu G Fillman, Maree J Webster, Cynthia Shannon Weickert |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21829518/?tool=EBI |
Similar Items
-
Increases in [3H]muscimol and [3H]flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to α4 and γ2S mRNA levels respectively.
by: Mathieu Verdurand, et al.
Published: (2013-01-01) -
Effects of memantine on the excitation-inhibition balance in prefrontal cortex
by: Nadezhda V. Povysheva, et al.
Published: (2016-12-01) -
Developmental trajectory of the endocannabinoid system in human dorsolateral prefrontal cortex
by: Long Leonora E, et al.
Published: (2012-07-01) -
Developmental patterns of doublecortin expression and white matter neuron density in the postnatal primate prefrontal cortex and schizophrenia.
by: Samantha J Fung, et al.
Published: (2011-01-01) -
Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia
by: Weickert Cynthia, et al.
Published: (2009-05-01)