Variants in clopidogrel-relevant genes and early neurological deterioration in ischemic stroke patients receiving clopidogrel

Variants in clopidogrel-relevant genes and early neurological deterioration in ischemic stroke patients receiving clopidogrel

Abstract Background Early neurological deterioration (END) is common in acute ischemic stroke (IS). However, the underlying mechanisms for END are unclear. The aim of this study was to evaluate the associations of 16 variants in clopidogrel-relevant genes and interactions among these variants with E...

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Bibliographic Details
Main Authors: Xingyang Yi, Qiang Zhou, Yongyin Zhang, Ju Zhou, Jing Lin
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Neurology
Subjects:
Ischemic stroke
Early neurological deterioration
Clopidogrel
Genetic polymorphism
Platelet membrane receptor
Glycoprotein IIIa
Online Access:http://link.springer.com/article/10.1186/s12883-020-01703-6

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