Glucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In Situ (DCIS) Suggests Metabolic Heterogeneity

Glucose Uptake and Intracellular pH in a Mouse Model of Ductal Carcinoma In Situ (DCIS) Suggests Metabolic Heterogeneity

Mechanisms for the progression of ductal carcinoma in situ (DCIS) to invasive breast carcinoma remain unclear. Previously we showed that the transition to invasiveness in the mammary intraepithelial neoplastic outgrowth (MINO) model of DCIS does not correlate with its serial acquisition of genetic m...

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Bibliographic Details
Main Authors:	Rebecca C. Lobo, Neil E. Hubbard, Patrizia Damonte, Hidetoshi Mori, Zsófia Pénzváltó, Cynthia Pham, Amanda L. Koehne, Aiza C. Go, Steve E. Anderson, Peter M. Cala, Alexander D Borowsky
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-08-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	Tumor Microenvironment intracellular pH ductal carcinoma in situ glucose uptake tumor heterogeneity mouse mammary carcinoma model
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00093/full

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