Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub>
Metalloporphyrins are highly recognized for their capacity to act as sensitive substances used in formulation of optical, fluorescent, and electrochemical sensors. A novel compound, namely Pt(II)-5,10,15,20-tetra-(4-allyloxy-phenyl) porphyrin, was synthesized by metalation with PtCl<sub>2</...
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doaj-9e949ac8ea24479b89c552e9d2ce45412020-11-25T03:31:50ZengMDPI AGChemosensors2227-90402020-04-018292910.3390/chemosensors8020029Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub>Eugenia Fagadar-Cosma0Nicoleta Plesu1Anca Lascu2Diana Anghel3Maria Cazacu4Catalin Ianasi5Gheorghe Fagadar-Cosma6Ion Fratilescu7Camelia Epuran8“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, RomaniaInstitute of Macromolecular Chemistry “Petru Poni”, Grigore Ghica Vodă Alley, No. 41A, 700487 Iasi, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, RomaniaFaculty of Industrial Chemistry and Environmental Engineering, Politehnica University of Timisoara, Vasile Pârvan Ave., No. 6, RO 300223 Timisoara, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, Romania“Coriolan Dragulescu” Institute of Chemistry of Romanian Academy, Mihai Viteazu Ave., No. 24, 300223 Timisoara, RomaniaMetalloporphyrins are highly recognized for their capacity to act as sensitive substances used in formulation of optical, fluorescent, and electrochemical sensors. A novel compound, namely Pt(II)-5,10,15,20-tetra-(4-allyloxy-phenyl) porphyrin, was synthesized by metalation with PtCl<sub>2</sub>(PhCN)<sub>2</sub> of the corresponding porphyrin base and was fully characterized by UV-vis, fluorimetry, FT-IR, <sup>1</sup>H-NMR, and <sup>13</sup>C-NMR methods. The fluorescence response of this Pt-porphyrin in the presence of different concentrations of hydrogen peroxide was investigated. Besides, modified glassy carbon electrodes with this Pt-porphyrin (Pt-Porf-GCE) were realized and several electrochemical characterizations were comparatively performed with bare glassy carbon electrodes (GCE), in the absence or presence of hydrogen peroxide. The Pt-porphyrin demonstrated to be a successful sensitive material for the detection of hydrogen peroxide both by fluorimetric method in a concentration range relevant for biological samples (1.05–3.9 × 10<sup>−7</sup> M) and by electrochemical method, in a larger concentration range from 1 × 10<sup>−6</sup> M to 5 × 10<sup>−5</sup> M. Based on different methods, this Pt-porphyrin can cover detection in diverse fields, from medical tests to food and agricultural monitoring, proving high accuracy (correlation coefficients over 99%) in both fluorimetric and electrochemical measurements.https://www.mdpi.com/2227-9040/8/2/29Pt-porphyrinphotoactive materialUV-vis spectroscopyfluorimetryelectrochemistryhydrogen peroxide detection |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Eugenia Fagadar-Cosma Nicoleta Plesu Anca Lascu Diana Anghel Maria Cazacu Catalin Ianasi Gheorghe Fagadar-Cosma Ion Fratilescu Camelia Epuran |
spellingShingle |
Eugenia Fagadar-Cosma Nicoleta Plesu Anca Lascu Diana Anghel Maria Cazacu Catalin Ianasi Gheorghe Fagadar-Cosma Ion Fratilescu Camelia Epuran Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> Chemosensors Pt-porphyrin photoactive material UV-vis spectroscopy fluorimetry electrochemistry hydrogen peroxide detection |
author_facet |
Eugenia Fagadar-Cosma Nicoleta Plesu Anca Lascu Diana Anghel Maria Cazacu Catalin Ianasi Gheorghe Fagadar-Cosma Ion Fratilescu Camelia Epuran |
author_sort |
Eugenia Fagadar-Cosma |
title |
Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> |
title_short |
Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> |
title_full |
Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> |
title_fullStr |
Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> |
title_full_unstemmed |
Novel Platinum-Porphyrin as Sensing Compound for Efficient Fluorescent and Electrochemical Detection of H<sub>2</sub>O<sub>2</sub> |
title_sort |
novel platinum-porphyrin as sensing compound for efficient fluorescent and electrochemical detection of h<sub>2</sub>o<sub>2</sub> |
publisher |
MDPI AG |
series |
Chemosensors |
issn |
2227-9040 |
publishDate |
2020-04-01 |
description |
Metalloporphyrins are highly recognized for their capacity to act as sensitive substances used in formulation of optical, fluorescent, and electrochemical sensors. A novel compound, namely Pt(II)-5,10,15,20-tetra-(4-allyloxy-phenyl) porphyrin, was synthesized by metalation with PtCl<sub>2</sub>(PhCN)<sub>2</sub> of the corresponding porphyrin base and was fully characterized by UV-vis, fluorimetry, FT-IR, <sup>1</sup>H-NMR, and <sup>13</sup>C-NMR methods. The fluorescence response of this Pt-porphyrin in the presence of different concentrations of hydrogen peroxide was investigated. Besides, modified glassy carbon electrodes with this Pt-porphyrin (Pt-Porf-GCE) were realized and several electrochemical characterizations were comparatively performed with bare glassy carbon electrodes (GCE), in the absence or presence of hydrogen peroxide. The Pt-porphyrin demonstrated to be a successful sensitive material for the detection of hydrogen peroxide both by fluorimetric method in a concentration range relevant for biological samples (1.05–3.9 × 10<sup>−7</sup> M) and by electrochemical method, in a larger concentration range from 1 × 10<sup>−6</sup> M to 5 × 10<sup>−5</sup> M. Based on different methods, this Pt-porphyrin can cover detection in diverse fields, from medical tests to food and agricultural monitoring, proving high accuracy (correlation coefficients over 99%) in both fluorimetric and electrochemical measurements. |
topic |
Pt-porphyrin photoactive material UV-vis spectroscopy fluorimetry electrochemistry hydrogen peroxide detection |
url |
https://www.mdpi.com/2227-9040/8/2/29 |
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