Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types
Genes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes.
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2016-01-01
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Online Access: | https://doi.org/10.1038/ncomms10499 |
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doaj-9e9f2de49587431ca557e2f3f464ca042021-05-11T10:47:38ZengNature Publishing GroupNature Communications2041-17232016-01-017111210.1038/ncomms10499Systematic identification of genes with a cancer-testis expression pattern in 19 cancer typesCheng Wang0Yayun Gu1Kai Zhang2Kaipeng Xie3Meng Zhu4Ningbin Dai5Yue Jiang6Xuejiang Guo7Mingxi Liu8Juncheng Dai9Linxiang Wu10Guangfu Jin11Hongxia Ma12Tao Jiang13Rong Yin14Yankai Xia15Li Liu16Shouyu Wang17Bin Shen18Ran Huo19Qianghu Wang20Lin Xu21Liuqing Yang22Xingxu Huang23Hongbing Shen24Jiahao Sha25Zhibin Hu26State Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityDepartment of Bioinformatics, School of Basic Medical Sciences, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityJiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University Affiliated Cancer HospitalDepartment of Molecular Cell Biology and Toxicology, Jiangsu Key Lab of Cancer Biomarkers, Prevention & Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical UniversityDigestive Endoscopy Center, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Molecular Cell Biology and Toxicology, Jiangsu Key Lab of Cancer Biomarkers, Prevention & Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityDepartment of Bioinformatics, School of Basic Medical Sciences, Nanjing Medical UniversityJiangsu Key Laboratory of Molecular and Translational Cancer Research, Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University Affiliated Cancer HospitalDepartment of Molecular and Cellular Oncology, Cancer Biology Program, Center for RNA Interference and Non-Coding RNAs, the University of Texas MD Anderson Cancer CenterSchool of Life Science and Technology, Shanghai Tech UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityState Key Laboratory of Reproductive Medicine, Nanjing Medical UniversityGenes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes.https://doi.org/10.1038/ncomms10499 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cheng Wang Yayun Gu Kai Zhang Kaipeng Xie Meng Zhu Ningbin Dai Yue Jiang Xuejiang Guo Mingxi Liu Juncheng Dai Linxiang Wu Guangfu Jin Hongxia Ma Tao Jiang Rong Yin Yankai Xia Li Liu Shouyu Wang Bin Shen Ran Huo Qianghu Wang Lin Xu Liuqing Yang Xingxu Huang Hongbing Shen Jiahao Sha Zhibin Hu |
spellingShingle |
Cheng Wang Yayun Gu Kai Zhang Kaipeng Xie Meng Zhu Ningbin Dai Yue Jiang Xuejiang Guo Mingxi Liu Juncheng Dai Linxiang Wu Guangfu Jin Hongxia Ma Tao Jiang Rong Yin Yankai Xia Li Liu Shouyu Wang Bin Shen Ran Huo Qianghu Wang Lin Xu Liuqing Yang Xingxu Huang Hongbing Shen Jiahao Sha Zhibin Hu Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types Nature Communications |
author_facet |
Cheng Wang Yayun Gu Kai Zhang Kaipeng Xie Meng Zhu Ningbin Dai Yue Jiang Xuejiang Guo Mingxi Liu Juncheng Dai Linxiang Wu Guangfu Jin Hongxia Ma Tao Jiang Rong Yin Yankai Xia Li Liu Shouyu Wang Bin Shen Ran Huo Qianghu Wang Lin Xu Liuqing Yang Xingxu Huang Hongbing Shen Jiahao Sha Zhibin Hu |
author_sort |
Cheng Wang |
title |
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
title_short |
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
title_full |
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
title_fullStr |
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
title_full_unstemmed |
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
title_sort |
systematic identification of genes with a cancer-testis expression pattern in 19 cancer types |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2016-01-01 |
description |
Genes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes. |
url |
https://doi.org/10.1038/ncomms10499 |
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