Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodinium cohnii

Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodinium cohnii

Abstract Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity. In recent years, repeated fed-batch strategies have been evaluated for in...

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Bibliographic Details
Main Authors: Liangsen Liu, Fangzhong Wang, Guangsheng Pei, Jinyu Cui, Jinjin Diao, Mingming Lv, Lei Chen, Weiwen Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Microbial Cell Factories
Subjects:
Repeated fed-batch culture
Docosahexaenoic acid
Productivity
Metabolomic
Stability
Crypthecodinium cohnii
Online Access:http://link.springer.com/article/10.1186/s12934-020-01349-6

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