MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)

MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)

This experiment was performed to examine the effects of Andrographis paniculata Nees leaves extract on foetus morphology if given during organogenesis period. Thirty pregnant mice were randomly divided into 5 groups for teratogenic effects. Extract was given orally by gavage with 0 (as control); 0,0...

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Main Author: IRIANI SETYAWATI
Format: Article
Language:English
Published: Universitas Udayana 2014-08-01
Series:Jurnal Biologi Udayana
Subjects:
Andrographis paniculata Nees
foetus morphology
Online Access:http://ojs.unud.ac.id/index.php/BIO/article/view/583
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spelling doaj-9eb8d5b041a3496e8b093cd8421c45ba2020-11-25T01:05:22ZengUniversitas UdayanaJurnal Biologi Udayana1410-52922014-08-01132556MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)IRIANI SETYAWATIThis experiment was performed to examine the effects of Andrographis paniculata Nees leaves extract on foetus morphology if given during organogenesis period. Thirty pregnant mice were randomly divided into 5 groups for teratogenic effects. Extract was given orally by gavage with 0 (as control); 0,004 (equal to one time dose to human); 7,5; 15; and 22,5 g/g body weight/ day. Treatment was given from day 6 to day 13 of gestation (organogenesis period). Foetus were removed on day 18 of gestation by caesarean section. Quantitative data were analyzed with Anova and Duncan's Multiple Range Test. The results showed that teratogenic effects increased in dose-related manner by causing foetus death and resorption, hemorrhage and clubfoot.http://ojs.unud.ac.id/index.php/BIO/article/view/583Andrographis paniculata Neesfoetus morphology
collection DOAJ
language English
format Article
sources DOAJ
author IRIANI SETYAWATI
spellingShingle IRIANI SETYAWATI
MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
Jurnal Biologi Udayana
Andrographis paniculata Nees
foetus morphology
author_facet IRIANI SETYAWATI
author_sort IRIANI SETYAWATI
title MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
title_short MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
title_full MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
title_fullStr MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
title_full_unstemmed MORFOLOGI FETUS MENCIT (MUS MUSCULUS L.) SETELAH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NEES)
title_sort morfologi fetus mencit (mus musculus l.) setelah pemberian ekstrak daun sambiloto (andrographis paniculata nees)
publisher Universitas Udayana
series Jurnal Biologi Udayana
issn 1410-5292
publishDate 2014-08-01
description This experiment was performed to examine the effects of Andrographis paniculata Nees leaves extract on foetus morphology if given during organogenesis period. Thirty pregnant mice were randomly divided into 5 groups for teratogenic effects. Extract was given orally by gavage with 0 (as control); 0,004 (equal to one time dose to human); 7,5; 15; and 22,5 g/g body weight/ day. Treatment was given from day 6 to day 13 of gestation (organogenesis period). Foetus were removed on day 18 of gestation by caesarean section. Quantitative data were analyzed with Anova and Duncan's Multiple Range Test. The results showed that teratogenic effects increased in dose-related manner by causing foetus death and resorption, hemorrhage and clubfoot.
topic Andrographis paniculata Nees
foetus morphology
url http://ojs.unud.ac.id/index.php/BIO/article/view/583
work_keys_str_mv AT irianisetyawati morfologifetusmencitmusmusculuslsetelahpemberianekstrakdaunsambilotoandrographispaniculatanees
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