FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression

<p>Abstract</p> <p>Background</p> <p>FGF signalling regulates numerous aspects of early embryo development. During gastrulation in amniotes, epiblast cells undergo an epithelial to mesenchymal transition (EMT) in the primitive streak to form the mesoderm and endoderm. I...

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Bibliographic Details
Main Authors: Konieczka JH, Yatskievych Tatiana A, Hardy Katharine M, Bobbs Alexander S, Antin Parker B
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/11/20