A Mediterranean Dietary Intervention in Female Carriers of BRCA Mutations: Results from an Italian Prospective Randomized Controlled Trial

A Mediterranean Dietary Intervention in Female Carriers of BRCA Mutations: Results from an Italian Prospective Randomized Controlled Trial

<i>Background:</i> Women carriers of <i>BRCA1</i>/<i>2 </i>mutations face a high lifetime risk (penetrance) of developing breast and/or ovarian cancer. Insulin-like growth factor I (IGF-I), body weight and markers of insulin resistance affect BRCA penetrance. We c...

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Bibliographic Details
Main Authors: Eleonora Bruno, Andreina Oliverio, Angelo Virgilio Paradiso, Antonella Daniele, Stefania Tommasi, Antonio Tufaro, Daniela Andreina Terribile, Stefano Magno, Alessio Filippone, Elisabetta Venturelli, Daniele Morelli, Ivan Baldassari, Maria Luisa Cravana, Siranoush Manoukian, Patrizia Pasanisi
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
randomized controlled trial
<i>BRCA1</i>/<i>2</i> mutations
mediterranean diet
insulin-like growth factor I
penetrance
personalized medicine
Online Access:https://www.mdpi.com/2072-6694/12/12/3732

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