Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy.

Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy.

We previously reported that synthetic vaccine particles (SVP) encapsulating antigens and TLR agonists resulted in augmentation of immune responses with minimal production of systemic inflammatory cytokines. Here we evaluated two different polymer formulations of SVP-encapsulated antigens and tested...

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Bibliographic Details
Main Authors: Petr O Ilyinskii, Grigoriy I Kovalev, Conlin P O'Neil, Christopher J Roy, Alicia M Michaud, Natalia M Drefs, Mikhail A Pechenkin, Fen-Ni Fu, Lloyd P M Johnston, Dmitry A Ovchinnikov, Takashi Kei Kishimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983463?pdf=render

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