METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome

METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome

Down syndrome (DS) is a common genetic condition in which a person is born with an extra copy of chromosome 21. Intellectual disability is the most common characteristic of DS. N6-methyladenosine (m6A) is a common RNA modification that is implicated in many biological processes. It is highly enriche...

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Bibliographic Details
Main Authors: Weili Shi, Fan Yang, Ranran Dai, Yafei Sun, Yan Chu, Shixiu Liao, Bingtao Hao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Down syndrome
NRIP1
m6A modification
METTL3
cerebral cortex
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.621374/full

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