The Role of Cancer-Associated Fibroblasts and Extracellular Vesicles in Tumorigenesis

The Role of Cancer-Associated Fibroblasts and Extracellular Vesicles in Tumorigenesis

Extracellular vesicles (EVs) play a key role in the communication between cancer cells and stromal components of the tumor microenvironment (TME). In this context, cancer cell-derived EVs can regulate the activation of a CAF phenotype in TME cells, which can be mediated by several EV cargos (e.g., m...

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Bibliographic Details
Main Authors:	Issraa Shoucair, Fernanda Weber Mello, James Jabalee, Saeideh Maleki, Cathie Garnis
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	International Journal of Molecular Sciences
Subjects:	extracellular vesicles tumor microenvironment cancer-associated fibroblasts neoplasms
Online Access:	https://www.mdpi.com/1422-0067/21/18/6837

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